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. 2025 Jul;43(7):1520-1522.
doi: 10.1016/j.tibtech.2025.05.005. Epub 2025 May 19.

Plant genome editing goes viral

Muhammad Waseem Sajjad  1 , Rubab Zahra Naqvi  1 , Imran Amin  2
Affiliations

Plant genome editing goes viral

Muhammad Waseem Sajjad et al. Trends Biotechnol. 2025 Jul.

Abstract

In a recent study, Weiss et al. presented an RNA virus-based system that transmits the compact genome editor TnpB into Arabidopsis thaliana, resulting in transgene-free and heritable modifications. This innovation transforms DNA delivery methods in plant biotechnology, providing a more straightforward, scalable, and regulatory-compliant approach to genome engineering.

Keywords: TnpB; Tobacco rattle virus (TRV); agroflooding; heritable editing; transgene-free editing; viral delivery.

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Conflict of interest statement

Declaration of interests The authors have no interests to declare.

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