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Editorial
. 2025 Dec;47(1):2503514.
doi: 10.1080/0886022X.2025.2503514. Epub 2025 May 20.

Are your kidneys ok? Detect early to protect kidney health

Affiliations
Editorial

Are your kidneys ok? Detect early to protect kidney health

Joseph A Vassalotti et al. Ren Fail. 2025 Dec.

Abstract

Early identification of kidney disease can protect kidney health, prevent kidney disease progression and related complications, reduce cardiovascular disease risk and decrease mortality. We must ask "Are your kidneys ok?" using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. Evaluation for causes and risk factors for chronic kidney disease (CKD) includes testing for diabetes and measurement of blood pressure and body mass index. This World Kidney Day we assert that case-finding in high-risk populations, or even population level screening, can decrease the burden of kidney disease globally. Early-stage CKD is asymptomatic, simple to test for and recent paradigm shifting CKD treatments such as sodium glucose co-transporter-2 inhibitors dramatically improve outcomes and favor the cost-benefit analysis for screening or case-finding programs. Despite this, numerous barriers exist, including resource allocation, healthcare funding, healthcare infrastructure and healthcare-professional and population awareness of kidney disease. Coordinated efforts by major kidney non-governmental organizations to prioritize the kidney health agenda for governments and aligning early detection efforts with other current programs will maximize efficiencies.

Keywords: Screening; albuminuria; case finding; chronic kidney disease; prevention; proteinuria.

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Risk factors for CKD.
Figure 2.
Figure 2.
Conceptual framework of a CKD testing, risk stratification, and treatment program, see reference [30].

References

    1. Ndumele CE, Neeland IJ, Tuttle KR, et al. . A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American Heart Association. Circulation. 2023;148(20):1636–1664. doi: 10.1161/CIR.0000000000001186. - DOI - PubMed
    1. Luyckx VA, Tuttle KR, Abdellatif D, et al. . Mind the gap in kidney care: translating what we know into what we do. Kidney Int. 2024;105(3):406–417. doi: 10.1016/j.kint.2023.12.003. - DOI - PubMed
    1. Stevens PE, Ahmed SB, Carrero JJ, et al. . KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int. 2024;105(4):S117–S314. doi: 10.1016/j.kint.2023.10.018. - DOI - PubMed
    1. Guha C, Lopez-Vargas P, Ju A, et al. . Patient needs and priorities for patient navigator programmes in chronic kidney disease: a workshop report. BMJ Open. 2020;10(11):e040617. doi: 10.1136/bmjopen-2020-040617. - DOI - PMC - PubMed
    1. Collaboration GBDCKD . Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709–733. - PMC - PubMed

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