Towards a common approach for managing food allergy and serious allergic reactions (anaphylaxis) at school. GA2LEN and EFA consensus statement
- PMID: 40397524
- PMCID: PMC11682877
- DOI: 10.1002/clt2.70013
Towards a common approach for managing food allergy and serious allergic reactions (anaphylaxis) at school. GA2LEN and EFA consensus statement
Abstract
GA2LEN and EFA propose minimum specifications for all industrialised countries/regions to work towards to support students with food allergies in educational settings. We reviewed research and legislation and gained feedback from over 100 patient and professional groups. We built shared expectations around: 1. training all school staff about what food allergy is, the symptoms of allergic reactions, what to do in an emergency, and when and how to use and store devices that laypeople can use to administer adrenaline (epinephrine). 2. preventing allergic reactions by using clear labelling on school menus and prepacked and non-prepacked foods and regular cleaning where students eat. 3. preparing for serious allergic reactions, with written emergency action plans for every student with food allergies, legislation allowing schools to store adrenaline for anyone who needs it in an emergency (not just those prescribed it), and training and legal safeguards for staff administering adrenaline. 4. including affected students by discussing food allergy in the curriculum, raising awareness among all students and caregivers and reviewing school processes regularly. It is time for national and international action at the policy level. Patient groups, education networks and professional societies all play a role in campaigning for shared next steps.
Keywords: anaphylaxis; food allergy; health education; long‐term management; school health service.
© 2024 The Author(s). Clinical and Translational Allergy published by John Wiley & Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.
Conflict of interest statement
Antoine Deschildre declared consulting fees from Novartis, GSK, Sanofi, Regeneron, AstraZeneca, Aimmune Therapeutics, Stallergenes Greer, ALK, Viatris, Celltryon; advisory board for BOOM study NCT04045301, all outside the submitted work. Montserrat Alvaro Lozano declared no interests. Antonella Muraro declared speaker fees for Aimmune, DBV Technologies, Nestlè Health Science, Nestlè Purina; advisory boards for Aimmune, Sanofi, DBV Technologies, Novartis, Regeneron, Viatris, all outside the submitted work. Marcia Podesta declared institutional grants from Viatris, DBV Technologies, Novartis, Aimmune; honoraria from DBV Technologies; advisory board for Novartis; president Food Allergy Italia, member GA2LEN ANACare Patient Advocates team, board member EAACI Patient Organisation Committee, member EAACI ethics committee, member FAO WHO Codex Alimentarius Commission. Member EAACI task forces and guideline groups, all outside the submitted work. Debra de Silva declared institutional funds from GA²LEN towards drafting the manuscript. Mattia Giovannini reports personal fees from Sanofi, outside the submitted work. Simona Barni declared speaker fees from Nutricia, Sanofi, all outside the submitted work. Timothy E. Dribin declared grants from the National Institutes of Health, outside the submitted work. Mónica Sandoval‐Ruballos declared no interests. Aikaterini Anagnostou declared institutional grants from Novartis, AAFA, Mike Hogg Foundation; advisory boards for Ready Set Food, Novartis, Genentech, Bryn and consulting/speaker fees ALK, EPG Health, MJH, Adelphi, Aimmune Therapeutics, Genentech, FARE, Medscape, Innovation horizons, all outside the submitted work. Alessandro Fiocchi declared grants from Novartis, Ferrero, Sanofi, Stallergenes, Danone, Aimmune; consulting fees or honoraria from Abbott, Ferrero, Sanofi; board or leadership positions at World Allergy Organisation, American Academy of Allergy Asthema and Immunology, all outside submitted work. Alice Toniolo declared no interests. Andrew Bird declared institutional grants from Aimmune, Astellas, DBV Technologies, FARE, Genentech, NIH NIAID, Novartis, Regeneron and Siolta; consulting from Allakos, AllerGenis, Allergy Therapeutics, DBV Technologies, FARE, Genentech, HAL Allergy, Novartis, Nutricia and Parexel; speaking fees from DBV Technologies; data monitoring board for Infinant Health, all outside the submitted work. Angel Sánchez Sanz declared institutional payments for speaker fees from Aimmune Therapeutics and Advisory Board for Novartis Pharma AG. Anna Asarnoj declared grants/nn‐commercial contracts from Karolinska Institutet, Swedish Asthma and Allergy Association’s Research Foundation, Swedish Association for Allergology, Swedish Society of Medicine, speaker fees from Orion Pharma, Nestlé, Aimmune Therapeutics, Semper, ThermoFisher, Scandinavian Biopharma, ALK; peer review fees for PHRGOC24jan‐0004 Singapore; advisory board for Novartis, Sanofi, Danone, Nestlé, ALK; unpaid board member for SFFA, Research Council for the Foundation for Child Research, editorial board Pediatrician, education committee of Swedish Peediatric Society, all outside the submitted work. Anna Nowak‐Wegrzyn declared board roles at AAAAI, IFPIES, all outside the submitted work. Berber Vlieg‐Boerstra declared research grant from Nutricia Research; speaker fees or honoraria from Nestle, Nutricia; advisory board for Vinimini, all outside the submitted work. Brian P. Vickery declared institutional grants/contracts from Aimmune, Alladapt, Aravax, AstraZeneca, DBV Technologies, FARE , Genentech, Novartis, NIH‐NIAID, Regeneron, Siolta; consulting fees from Aimmune, Allergenis, Allakos, Aravax, Genentech, IgGenix, Novartis, Parexel, Reacta, Regeneron, Revolo, Sanofi, Sattergenes Greer; stock in Moonlight Therapeutics, all outside the submitted work. Carina Venter declared grant from Reckitt, speaker fees for Reckitt, Danone, Abbott, Nestle Nutrition Institute, all outside the submitted work. Caroline Nilsson declared institutional grant from Aimmune; institutional equipment from Thermofisher, honoraria to institution from ALK, GSK, Thermofisher; advisory board Aimmune, all outside the submitted work. Cecila Parente declared no interests. Céline Demoulin declared institutional grants or contracts from Aimmune, ALK, Bioprojet, DBV Technologies. Stallergenes Greer, Novartis, Thermo Fisher, Viatris Sante, all outside the submitted work. David M Fleischer declared institutional funding from ARS Pharmaceuticals, DBV Technologies; consultancy fees from Aquestive, ARS Pharmaceuticals, Byrn Pharma, DBV Technologies Genentech, Nasus; speaker fees from Genentech; royalties from UpTodate; stock options from Grow Happy, all outside the submitted work. Diola Bijhout declared no interests. Edward F. Knol declared no interests. Eleanor Garrow declared no interests. Emma E. Cook declared grant from JSPS Grant‐in‐Aid for Scientific Research; institutional consulting for Novartis Global Food Allergy Patient Council, outside the submitted work. Fallon Shulz declared no interests. Francesca Lazzarotto declared no interests. Francesca Mori declared consulting fees from ALK‐Abello, Aboca, all outside the submitted work. Gideon Lack declared institutional grants from National Institute of Allergy and Infectious Diseases, National Peanut Board; consulting fees from Novartis, DBV Technologies, Reckitt Mead Johnson, ALK Abello; speaker fees from DBV Technologies, Aimmune, EPG Health; stock in DBV Technologies, Mighty MissionMe, all outside the submitted work. Graham Roberts declared grants from NIHR, Food Standards Agency, Action medical Research, NIH; honoraria from ALK‐Abello, ThermoFisher; past president of BSACI, all outside the submitted work. Guillaume Pouessel declared consulting fees from Bioprojet, Theravia, Viatris, all outside the submitted work. Gustavo Andres Marino declared no interests. Helen Brough declared institutional research grants from National Institute of Allergy and Infectious Disease, DBV Technologies, Aimmune; advisory boards for Consortium for Food Allergy Research, National Institute for Allergy and Infectious Disease, National Institute for Health and Care Research, consultancy/speaker fees from DBV Technologies, Viatris, Parexel, Stallergenes, all outside the submitted work. Hugh A. Sampson declared institutional grants from NIAID, NIH, FARE; royalties from Wiley; consulting fees/honoraria from AAAAi, DBV Technologies, FARE, N‐Fold LLC, Alpina Biotech; advisory board for Siolta Therapeutics, FARE; stock from DBV Technologies, N‐Fold LLC all outside the submitted work. Jay Lieberman declared consulting fees from ARS, Aquestive, Bryn; honoraria from Medscape; leadership role for Joint Task Force for Practice Parameters, American Board of Allergy and Immunology, all outside the submitted work. Jennifer Gerdts declared institutional grants from National Peanut Board, Pfizer Canada, all outside the submitted work. Jing Zhao declared no interests. Josefine Gradman declared no conflict of interest. Julia E. M. Upton declared institutional grants from DBV Technologies, Alk‐Abello; institutional equipment from Novartis; consulting fees/honoraria from Pharming N.V, Pfizer, Viatris, Astra Zeneca, Bausch Health; member of Health Care Advisory Board Food Allergy Canada, editorial board Allergy, editorial board Annals of Allergy Asthma and Immunology; unpaid leadership role at CSACI, all outside the submitted work. Julie Wang declared institutional grants from Aimmune, DBV, Siolta, NIH; royalties from UpToDate; consulting fees from DBV, Novartis, all outside the submitted work. Kati Palosuo declared no interests. Kirsi M Järvinen declared grants to institution from NiAID, Janssen R&D, Aimmune, royalties from Wolter Klower, consulting fees from Harmony / Milk Care, Janseen R&D, speaker fees from AAAAI, all outside the submitted work. Kirsten Beyer declared institutional grants from Danone, DBV, Hipp, Infectopharm, Hycor, Novartis; advisory boards for Aimmune, Danone, Mylan, Nestle, Allergy Therapeutics, Novartis, Kantar Health, Primus Consulting; consultation/speaker fees from Hipp, Novartis, Aimmune, ALK, Danone, Infectopharm, Nestle, Hycor, ThermoFisher, Limbach Gruppe, Kantar Health, Sonic Heathcare; unpaid leadership or committee roles at GPA, DGAKI, DAAB, AGATE, NORA, all outside the submitted work. Kunling Shen declared no interests. Laura Polloni declared no interests. Lianne Mandelbaum declared no interests. Luciana Kase Tanno declared Director of the WHO Collaborating Centre on Classification Scientific Support and board member of WHO Medical and Scientific Advisory Committee Board, World Allergy Organisation and French Allergy Society, all outside the submitted work. Lucy A Bilaver declared institutional grants from NIH, Genentech, Novartis, Yobee Care, Northwestern University NUCATS, all outside the submitted work. Marcus Shaker declared member of Joint Task Force on Practice Parameters; editorial board of Journal of Allergy and Clinical Immunology In Practice; associate editor of Annals of Allergy, Asthma, and Immunology; Board of Directors of American Academy of Allergy, Asthma, and Immunology, all outside the submitted work. Margitta Worm declared honoraria/consulting fees from AbbVie, Aimmune Therapeutics, ALK‐Abelló, Allergopharma, Almirall, Amgen, AstraZeneca, Biotest, Boehringer Ingelheim, Bristol‐Myers Squibb, DBV Technologies, GlaxoSmithKline, Genzyme, Kymab, LEO Pharma, Lilly, Mylan, Novartis, Pfizer, Regeneron Pharmaceuticals Inc., Sanofi‐Aventis, Stallergenes Greer, Worg Pharmaceutics, all outside the submitted work. Maria Said declared no interests. Mary Jane Marchisotto declared no interests. Mary Kelly declared no interests. Michael Makris declared honoraria from Astra Zeneca, GSK, Novartis, Pfizer, Sanofi‐Aventis; Monitoring Board for Pfizer, Astra Zeneca, GSK, all outside the submitted work. Mikaela Odemyr declared no interests. Montserrat Fernandez‐Rivas declared institutional grants from Instituto de Salud Carlos III (Spanish Goverment), Diater, Aimmune Therapeutics, Novartis; speaker fees from EPG Health, HAL Allergy GSK; consulting fees from DBV, Aimmune Therapeutics, Novartis, Reacta Healthcare, SPRIM, Viatris, all outside the submitted work. Motohiro Ebisawa declared no interests. Nandinee Patel declared no interests. Pablo Rodríguez del Río declared research grants from FAES, Aimmune Therapeutics; speaker fees from DBV, GSK, FAES, Novartis, ALK‐Abelló, LETI Pharma, Aimmune Therapeutics, Sanofi, Stallergenes; consultancy fees from FAES, Miravo, all outside the submitted work. Pakit Vichyanond declared no interests. Paul Turner declared grants from UK Medical Research Council, NIHR‐Imperial Biomedical Research Centre, UK Food Standards Agency, Jon Moulton Charity Trust; honoraria from UK Food Standards Agency, all outside the submitted work. Pete Smith declared grant from Viatris, GSK, Sanofi; speaker fees from Bayer, Danone, Viatris, GSK, AZ, Sanofi, Mundipharama, Nutricia; board for Nestle Nutrition Institute, all outside the submitted work. Pilar Moron Gaspar declared no interests. R. Sharon Chinthrajah declared grants from the Consortium for Food Allergy Research (CoFAR), National Institute of Allergy and Infectious Disease (NIAID), Food Allergy Research & Education (FARE); advisory board member for Alladapt Immunotherapeutics, Novartis, Allergenis, Intrommune Therapeutics, Phylaxis, Latitude, Genentech, all outside the submitted work. Rima Rachid declared grants from Novartis, Siolta Therapeutics, NIAID CoFAR, Food Allergy Fund; speakers fees / honoraria from Eli Lilly, Genentech, Novartis, Medscape, FARE, EFAAC, MAAC; patents US patent application PCT/US2016/060353, US patent application: 62/823,866, US patent application 62/758,161(62/798,224), US patent application 17/801,238; Vice Chair, Food Allergy and Eosinophilic disorders interest section, AAAAI, all outside the submitted work. Roberta Bonaguro declared no interests. Ruchi Gupta declared institutional funding from NIH, FARE, Melchioree Family Foundation, Sunshine Charitable Foundation, Genentech, Novartis; consulting fees from FARE, Genentech, Novartis, OWYN, Kaleo, Aquestive Therapies, Bryn Pharma, patents with Yobee U.S. Patent No. 11,103,544, ownership interest in Yobee Care Inc. Sabine Schnadt declared speaker fees from Aimmune Therapeutics, DBV Technologies, Mylan Germany, all outside the submitted work. Sakura Sato declared no interests. Stefania Arasi declared speaker/consultancy fees from Ulrich, DBV, Stallergenes Greer, Thermofischer Scientific; monitoring board for Novartis, Stallergenes Greer, all outside the submitted work. Stephanie Leonard declared institutional grants from Aimmune Therapeutics, DBV Technologies, Siolta Therapeutics, Stanford University; past employment, consulting fees and stock options from Hanimune Therapeutics; honoraria from American College of Allergy, Asthma and Immunology, San Diego Allergy Society, Washington State Society of Allergy, Asthma, and Immunology; advisory board Cour Pharmaceuticals Development Co, all outside submitted work. Sung Poblete declared no interests. Susanne Halken declared speaker fees from ALK‐Abello, Nestlé Purino, Abigo, Meadjohnson; monitoring committee for Stallergenes, all outside the submitted work. Thuy‐My Le declared grants from Dutch Research Council and Novartis; honariaria from Abbvie, Thermofisher Scientific, Abbvie, all outside the submitted work. Torsten Zuberbier declared grants from Novartis and Henkel, consulting fees from Bayer Health Care, FAES, Novartis, Henkel, speaker fees from AstraZeneca, AbbVie, ALK, Almirall, Astellas, Blueprint, Beyer Health care, Baiersdorf, Bencard, Berlin Chemie, FAES, HAL, Henkel, Kryolan, Leti, L’Oreal, Meda, Menarini, Merck, MSD, Novartis, Pfizer, Sanofi, Stallergenes, Takeda, Teva and UCB; Board member or lead of DGAKI and ECARF, all outside the submitted work. President of GA2LEN. Tracey Dunn declared no interests. Victoria Cardona declared no interests.
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