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. 1977 Apr;34(4):299-304.
doi: 10.1007/BF00996206.

Immunochemical and ultrastructural investigations in a patient with cold-agglutinine-active monoclonal IgMK-gammopathy

S Ottó, M Börzonyi, S Eckhardt, A Mohay, J Gergely, R Kellner

Immunochemical and ultrastructural investigations in a patient with cold-agglutinine-active monoclonal IgMK-gammopathy

S Ottó et al. Blut. 1977 Apr.

Abstract

A patient with "chronic cold-agglutinin disease" is described. Initially, the process was a benign monoclonal gammopathy. After an intervall of 6 years clinical, cytomorphological and immunochemical studies showed progress towards malignancy. In the bone marrow intranuclear lipid-like inclusions appeared in the plasma cells.

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