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Review
. 2025 Aug;70(8):1033-1044.
doi: 10.1089/respcare.13066. Epub 2025 May 21.

Year in Review: Pulmonary Function Testing

Affiliations
Review

Year in Review: Pulmonary Function Testing

Jeffrey M Haynes. Respir Care. 2025 Aug.

Abstract

Pulmonary function testing dates back to the 19th century, and the most commonly performed tests pre-date the use of computers. Despite its long and rich history, much is still unknown about how to best perform, interpret, and apply pulmonary function tests. This year-in-review article will discuss recently published papers covering important topics including the performance of lung volume testing, the definition and severity grading of air flow obstruction, the clinical utility of bronchodilator responsiveness, and the use of race-neutral reference equations.

Keywords: COPD; fractional exhaled nitric oxide; lung volumes; pulmonary function testing; reference ranges; spirometry.

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References

    1. Petty TL. John Hutchinson’s mysterious machine revisited. Chest 2002;121(5 Suppl):219S–223S; doi: 10.1378/chest.121.5_suppl.219s - DOI - PubMed
    1. Graham BL, Steenbruggen I, Miller MR, et al. Standardization of spirometry 2019 update. An official American thoracic society and European respiratory society technical statement. Am J Respir Crit Care Med 2019;200(8):e70–e88; doi: 10.1164/rccm.201908-1590ST - DOI - PMC - PubMed
    1. Graham BL, Brusasco V, Burgos F, et al. 2017 ERS/ATS standards for single-breath carbon monoxide uptake in the lung. Eur Respir J 2017;49(1):1600016; doi: 10.1183/13993003.00016-2016 - DOI - PubMed
    1. Coates AL, Wanger J, Cockcroft DW, et al. ; Bronchoprovocation Testing Task Force: Kai-Håkon Carlsen . ERS technical standard on bronchial challenge testing: General considerations and performance of methacholine challenge tests. Eur Respir J 2017;49(5):1601526; doi: 10.1183/13993003.01526-2016 - DOI - PubMed
    1. Hallstrand TS, Leuppi JD, Joos G, et al. ; American Thoracic Society (ATS)/European Respiratory Society (ERS) Bronchoprovocation Testing Task Force . ERS technical standard on bronchial challenge testing: Pathophysiology and methodology of indirect airway challenge testing. Eur Respir J 2018;52(5):1801033; doi: 10.1183/13993003.01033-2018 - DOI - PubMed

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