Hemodynamic Right Heart Catheterization Before Transcatheter Mitral and Tricuspid Therapies

Cosmo Godino¹, Antonio Sisinni², Luca Raone³, Francesco Maria Sparasci³, Andrea Munafò⁴, Alberto Margonato¹, Luca Testa², Maurizio Taramasso⁵, Fabien Praz⁶, Sami Alnasser⁷, Neil Fam⁷, Rodrigo Estevez-Loureiro⁸, Francesco Saia⁹, Francesco Bedogni², Azeem Latib¹⁰, Claudia Baratto^{11

12}, Francesca Coppi¹³, Marianna Adamo¹⁴, Altin Palloshi¹⁵, Gabriele Crimi¹⁶, Scott Lim¹⁷, Francesco Maisano¹⁵, Ryan J Tedford¹⁸, Sergio Caravita^{11

12}

Affiliations

¹ Cardiology Unit, Heart Valve Center, IRCCS Ospedale San Raffaele, Milano, Italy (C.G., A. Margonato).
² Cardiology Unit, IRCCS Policlinico San Donatoand Università degli studi di Milano, Italy (A.S., L.T., F.B.).
³ Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy (L.R., F.M.S.).
⁴ De Gasperis Cardio Center, Interventional Cardiology Unit, Niguarda Hospital, Milan, Italy (A. Munafò).
⁵ Herzzentrum Hirslanden Zurich, Klinik Hirslanden, Switzerland (M.T.).
⁶ Department of Cardiology, University Hospital Bern, Switzerland (F.P.).
⁷ Division of Cardiology, St. Michael's Hospital, University of Toronto, Ontario, Canada (S.A., N.F.).
⁸ Cardiology Department, University Hospital Alvaro Cunqueiro, Galicia Sur Health Research Institute, Vigo, Spain (R.E.-L.).
⁹ Interventional Cardiology Unit, IRCCS University Hospital of Bologna Policlinico S. Orsola, Italy (F.S.).
¹⁰ Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (A.L.).
¹¹ Division of Cardiology, Dyspnea and Pulmonary Hypertension Clinic, Ospedale San Luca IRCCS Istituto Auxologico, Italiano, Milano, Italy (C.B., S.C.).
¹² Department of Management, Information and Production Engineering, University of Bergamo, Italy (C.B., S.C.).
¹³ Division of Cardiology, Pulmonary Hypertension Program, Azienda Ospedaliera Policlinico di Modena, Italy (F.C.).
¹⁴ Cardiac Catheterization Laboratory and Cardiology, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Italy (M.A.).
¹⁵ Department of Cardiothoracic Surgery, Heart Valve Center, IRCCS Ospedale San Raffaele, Milano, Italy (A.P., F.M.).
¹⁶ DICATOV-Cardiothoracic and Vascular Department, San Martino Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy (G.C.).
¹⁷ Division of Cardiology, Department of Medicine, University of Virginia, Charlottesville (S.L.).
¹⁸ Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston (R.J.T.).

PMID: 40401405
DOI: 10.1161/CIRCHEARTFAILURE.124.012489

Review

Hemodynamic Right Heart Catheterization Before Transcatheter Mitral and Tricuspid Therapies

Cosmo Godino et al. Circ Heart Fail. 2025.

. 2025 May 22:e012489.

doi: 10.1161/CIRCHEARTFAILURE.124.012489. Online ahead of print.

Authors

Affiliations

¹ Cardiology Unit, Heart Valve Center, IRCCS Ospedale San Raffaele, Milano, Italy (C.G., A. Margonato).
² Cardiology Unit, IRCCS Policlinico San Donatoand Università degli studi di Milano, Italy (A.S., L.T., F.B.).
³ Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy (L.R., F.M.S.).
⁴ De Gasperis Cardio Center, Interventional Cardiology Unit, Niguarda Hospital, Milan, Italy (A. Munafò).
⁵ Herzzentrum Hirslanden Zurich, Klinik Hirslanden, Switzerland (M.T.).
⁶ Department of Cardiology, University Hospital Bern, Switzerland (F.P.).
⁷ Division of Cardiology, St. Michael's Hospital, University of Toronto, Ontario, Canada (S.A., N.F.).
⁸ Cardiology Department, University Hospital Alvaro Cunqueiro, Galicia Sur Health Research Institute, Vigo, Spain (R.E.-L.).
⁹ Interventional Cardiology Unit, IRCCS University Hospital of Bologna Policlinico S. Orsola, Italy (F.S.).
¹⁰ Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (A.L.).
¹¹ Division of Cardiology, Dyspnea and Pulmonary Hypertension Clinic, Ospedale San Luca IRCCS Istituto Auxologico, Italiano, Milano, Italy (C.B., S.C.).
¹² Department of Management, Information and Production Engineering, University of Bergamo, Italy (C.B., S.C.).
¹³ Division of Cardiology, Pulmonary Hypertension Program, Azienda Ospedaliera Policlinico di Modena, Italy (F.C.).
¹⁴ Cardiac Catheterization Laboratory and Cardiology, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Italy (M.A.).
¹⁵ Department of Cardiothoracic Surgery, Heart Valve Center, IRCCS Ospedale San Raffaele, Milano, Italy (A.P., F.M.).
¹⁶ DICATOV-Cardiothoracic and Vascular Department, San Martino Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy (G.C.).
¹⁷ Division of Cardiology, Department of Medicine, University of Virginia, Charlottesville (S.L.).
¹⁸ Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston (R.J.T.).

PMID: 40401405
DOI: 10.1161/CIRCHEARTFAILURE.124.012489

Abstract

Recent findings emphasize the potential role of invasive hemodynamic assessment in guiding transcatheter mitral and tricuspid valve percutaneous interventions. Right heart catheterization-derived parameters offer insights into hemodynamic changes associated with valvular heart diseases, pulmonary hypertension phenotyping, and right ventricular to pulmonary artery coupling. This might improve prognostic stratification for candidates to transcatheter therapies. This review provides a clinical overview of available data regarding the utility of preoperative right heart catheterization-derived parameters in patients undergoing mitral and tricuspid percutaneous repair or replacement.

Keywords: cardiac catheterization; heart valve diseases; hemodynamics; humans; prognosis.

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Hemodynamic Right Heart Catheterization Before Transcatheter Mitral and Tricuspid Therapies

Affiliations

Hemodynamic Right Heart Catheterization Before Transcatheter Mitral and Tricuspid Therapies

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Abstract

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