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. 2025 May 22;36(7):1680-1683.
doi: 10.1111/jce.16724. Online ahead of print.

Early Results of the New Pamira ICD Lead

Adrian Bystriansky  1 , Michael Ilan  2 , Ulrich Gerk  3 , Béla Merkely  4 , Attila Kónyi  5 , Martin Winterhalter  6 , Jozsef Faluközy  7 , Nicholas Jackson  8 , Avishag Laish-Farkash  9 , Nils Jenke  10 , Lars Anneken  11
Affiliations

Early Results of the New Pamira ICD Lead

Adrian Bystriansky et al. J Cardiovasc Electrophysiol. .

Abstract

Introduction: A new implantable cardioverter-defibrillator (ICD) lead with a polyurethane cover added for improved long-term reliance was investigated in a post-market study.

Methods: The prospective BIO|MASTER Pamira study is designed to evaluate the new Pamira ICD lead in patients undergoing de-novo ICD or cardiac resynchronization therapy (CRT-D) implantation. We report first data from implantation and 6-month follow-up.

Results: Despite its slightly larger diameter, the lead demonstrated similar or improved handling during implantation compared to its predecessor without polyurethane cover.

Conclusion: All results from implantation and short-term follow-up aligned with expectations. To show an improved reliance, long-term data will be required.

Keywords: implantable cardioverter defibrillator; lead handling; lead implantation; right ventricular lead; safety.

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Conflict of interest statement

Nils Jenke is an employee of Biotronik. All clinical authors received patient fees in the context of the study, which were paid to their institutions.

Figures

Figure 1
Figure 1
Design of the Pamira ICD lead (single‐coil model). ICD, implantable‐cardioverter defibrillator; PU, polyurethane.
Figure 2
Figure 2
Investigators' assessment of the leads' handling performance.
Figure 3
Figure 3
Pamira lead measurements. Of 205 patients reaching the 6‐month follow‐up, RV pacing threshold and RV sensing amplitude could not be measured in 1 and 3 patients, respectively, due to clinical reasons. RV, right ventricular.
See this image and copyright information in PMC

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