Critical appraisal of the 2 mm threshold in ductal carcinoma in situ: methodological concerns in meta-analysis of margin width and local recurrence risk
- PMID: 40405944
- PMCID: PMC12093165
- DOI: 10.21037/gs-2025-108
Critical appraisal of the 2 mm threshold in ductal carcinoma in situ: methodological concerns in meta-analysis of margin width and local recurrence risk
Keywords: Ductal carcinoma in situ (DCIS); breast cancer; recurrence; resection margins.
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://gs.amegroups.com/article/view/10.21037/gs-2025-108/coif). K.M. received research grant provided by Breast Cancer Charity, consulting fees from QMedical and Sebbin, and honoraria for offering academic and clinical advice to Merit Medical and QMedical corporations. He is a fractional shareholder of Datar Genetics stock. Furthermore, he owns shares in HCA Healthcare UK and OncoBotanica. The other authors have no conflicts of interest to declare.
Comment on
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Impact of resection margin width on local recurrence following breast-conserving surgery and whole breast radiotherapy for pure ductal carcinoma in situ: a systematic review and meta-analysis.BMJ Oncol. 2025 Mar 6;4(1):e000633. doi: 10.1136/bmjonc-2024-000633. eCollection 2025. BMJ Oncol. 2025. PMID: 40099004 Free PMC article.
References
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- Ezzat A, Shanthakumar D, Laskar N, et al. Impact of resection margin width on local recurrence following breast-conserving surgery and whole breast radiotherapy for pure ductal carcinoma in situ: a systematic review and meta-analysis. BMJ Oncol 2025;4:e000633. 10.1136/bmjonc-2024-000633 - DOI - PMC - PubMed
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