Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Aug;20(2):140-3.
doi: 10.1111/j.1365-2125.1985.tb05045.x.

The effects of long-acting pinacidil on intra-arterial blood pressure

M P Caruana, I Al-Khawaja, P Royston, E B Raftery

The effects of long-acting pinacidil on intra-arterial blood pressure

M P Caruana et al. Br J Clin Pharmacol. 1985 Aug.

Abstract

We have tested the efficacy of a new long-acting preparation of pinacidil, an arterial vasodilator, using continuous intra-arterial ambulatory blood pressure recording. An acute dose produced a measurable effect lasting for 12 h. The duration of this effect was less during chronic twice daily drug administration. Side effects were common, causing two out of nine patients to withdraw from the study. Tilt testing produced no postural hypotension and there was no evidence of rebound hypertension on the withdrawal day.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. N Engl J Med. 1976 Aug 5;295(6):320-3 - PubMed
    1. Med Biol Eng Comput. 1978 Nov;16(6):727-31 - PubMed
    1. J Cardiovasc Pharmacol. 1981 Sep-Oct;3(5):1002-7 - PubMed
    1. Clin Physiol. 1981 Aug;1(4):375-84 - PubMed
    1. Br J Clin Pharmacol. 1983 Sep;16(3):336-8 - PubMed