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Review
. 2025;90(2):154-157.
doi: 10.48095/cccg2025154.

Sister Mary Joseph's nodule - rare umbilical cutaneous metastasis

Markéta Polková, Pavel Kabele, Peter Koliba, Tadios Mekonnen Asres, Olga Dubová, Tomáš Brtnický, Michal Zikán
Review

Sister Mary Joseph's nodule - rare umbilical cutaneous metastasis

Markéta Polková et al. Ceska Gynekol. 2025.

Abstract

This is a short review about a rare metastatic physical finding of abdomino-pelvic malignancies that is called Sister Mary Joseph's nodule. It is cutaneous metastasis in the umbilical region and it was first used almost 200 years ago. Even though it is a rare finding, we should not forget it in the differential diagnosis of umbilical nodules. The article also includes two case reports.

Keywords: Sister Mary Joseph’s nodules; metastatic disease; skin metastases; umbilical lesion.

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