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. 2025 May 23;12(3):341-348.
doi: 10.1515/dx-2025-0006. eCollection 2025 Aug 1.

Implementation of a curriculum on communicating diagnostic uncertainty for clerkship-level medical students: a pseudorandomized and controlled study

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Implementation of a curriculum on communicating diagnostic uncertainty for clerkship-level medical students: a pseudorandomized and controlled study

Neha Bansal Etherington et al. Diagnosis (Berl). .

Abstract

Objectives: Physicians rarely receive formal training on communicating diagnostic uncertainty to patients. Best practices in timing and educational strategies are not established. We aimed to develop, implement and assess a curriculum on communicating uncertainty for medical students.

Methods: This was a pseudorandomized and controlled study. Students on their Internal Medicine Clerkship during the study period from February to August 2023 were invited to participate and separated into control and intervention groups based on assigned rotation site. Students in the intervention group received a curriculum on communicating diagnostic uncertainty. All students completed a subscale of the Physicians' Reaction to Uncertainty Scale (PRUS) at the beginning of their clerkship and at the end of week 4 and an Objective Structured Clinical Examination (OSCE) at the end of week 4.

Results: Fifty-four students participated in the curriculum (29 intervention, 25 control). Intervention group students scored 2.13 points higher than control group students on their skills assessment (mean OSCE for intervention group=14.3, control group=12.17, p<0.001). PRUS increased in both groups, indicating improved tolerance of uncertainty, with no significant difference in change in PRUS between groups (mean change in PRUS for intervention group=2.68, control group=4.82, p=0.33). 97.7 % of students agreed that a curriculum on uncertainty should be included in their medical training.

Conclusions: Students who participated in a curriculum on communication of uncertainty demonstrated superior skills in communicating uncertainty during their OSCE. There was a significant increase in PRUS indicating decreased stress associated with uncertainty for all students. This may reflect high levels of baseline stress associated with starting a clerkship, maturation, exposure to cases, or role-modeling by the clinical team.

Keywords: communication; curriculum; medical education; uncertainty.

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References

    1. Bhise, V, Rajan, SS, Sittig, DF, Morgan, RO, Chaudhary, P, Singh, H. Defining and measuring diagnostic uncertainty in medicine: a systematic review. J Gen Intern Med 2018;33:103–15. https://doi.org/10.1007/s11606-017-4164-1 . Epub 2017 Sep 21. - DOI
    1. Alam, R, Cheraghi-Sohi, S, Panagioti, M, Esmail, A, Campbell, S, Panagopoulou, E. Managing diagnostic uncertainty in primary care: a systematic critical review. BMC Fam Pract 2017;18:79. https://doi.org/10.1186/s12875-017-0650-0 . - DOI
    1. Hillen, MA, Gutheil, CM, Strout, TD, Smets, EMA, Han, PKJ. Tolerance of uncertainty: conceptual analysis, integrative model, and implications for healthcare. Soc Sci Med 2017;180:62–75. https://doi.org/10.1016/j.socscimed.2017.03.024 . Epub 2017 Mar 14. - DOI
    1. Hancock, J, Mattick, K. Tolerance of ambiguity and psychological well-being in medical training: a systematic review. Med Educ 2020;54:125–37. https://doi.org/10.1111/medu.14031 . Epub 2019 Dec 22. - DOI
    1. Stephens, GC, Sarkar, M, Lazarus, MD. I was uncertain, but I was acting on it’: a longitudinal qualitative study of medical students’ responses to uncertainty. Med Educ 2024;58:869–79. https://doi.org/10.1111/medu.15269 . - DOI

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