Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Apr 22;32(5):244.
doi: 10.3390/curroncol32050244.

Technical Innovations and Complex Cases in Robotic Surgery for Lung Cancer: A Narrative Review

Affiliations
Review

Technical Innovations and Complex Cases in Robotic Surgery for Lung Cancer: A Narrative Review

Giacomo Cusumano et al. Curr Oncol. .

Abstract

For over two decades, robotic-assisted thoracic surgery (RATS) has revolutionized thoracic oncology. With enhanced visualization, dexterity, and precision, RATS has reduced blood loss, shortened hospital stays, and sped up recovery compared to traditional surgery or video-assisted thoracoscopic surgery (VATS). The use of 3D high-definition imaging and articulated instruments allows for complex resections and advanced lymph node assessment. RATS delivers oncological outcomes similar to open surgery and VATS, with high rates of complete (R0) resections and acceptable complication rates. Its minimally invasive nature promotes quicker recovery. Advances in imaging software and augmented reality further enhance surgical accuracy and reduce intraoperative risks. However, RATS has some limitations, including high costs and a lack of tactile feedback, and certain complex procedures, such as extended resections and intrapericardial interventions, remain challenging. With growing experience and technological advances, RATS shows promise in reducing morbidity, improving quality of life, and expanding access to advanced oncologic care. This article reviews the evolution, benefits, and limitations of RATS in NSCLC treatment, highlighting its emerging role in managing complex cases.

Keywords: RATS; mini-invasive surgery; non-small cell lung cancer; robotic surgery.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
CT scan showing the target lesion.
Figure 2
Figure 2
Three-dimensional reconstruction showing the anatomical relationships of the tumor with the thoracic structures.

Similar articles

References

    1. Ma J., Li X., Zhao S., Wang J., Zhang W., Sun G. Robot-assisted thoracic surgery versus video-assisted thoracic surgery for lung lobectomy or segmentectomy in patients with non-small cell lung cancer: A meta-analysis. BMC Cancer. 2021;21:498. doi: 10.1186/s12885-021-08241-5. - DOI - PMC - PubMed
    1. Nelson D.B., Mehran R.J., Mitchell K.G., Rajaram R., Correa A.M., Bassett R.L., Jr., Antonoff M.B., Hofstetter W.L., Roth J.A., Sepesi B., et al. Robotic assisted lobectomy for non-small cell lung Cancer: A comprehensive institutional experience. Ann. Thorac. Surg. 2019;108:370–376. doi: 10.1016/j.athoracsur.2019.03.051. - DOI - PubMed
    1. Yang H.X., Woo K.M., Sima C.S., Bains M.S., Adusumilli P.S., Huang J., Finley D.J., Rizk N.P., Rusch V.W., Jones D.R., et al. Long-term Survival Based on the Surgical Approach to Lobectomy for Clinical Stage I Nonsmall Cell Lung Cancer: Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy. Ann. Surg. 2017;265:431–437. doi: 10.1097/SLA.0000000000001708. - DOI - PMC - PubMed
    1. Catelli C., Corzani R., Zanfrini E., Franchi F., Ghisalberti M., Ligabue T., Meniconi F., Monaci N., Galgano A., Mathieu F., et al. RoboticAssisted (RATS) versus Video-Assisted (VATS) lobectomy: A monocentric prospective randomized trial. Eur. J. Surg. Oncol. 2023;49:107256. doi: 10.1016/j.ejso.2023.107256. - DOI - PubMed
    1. Hong J.I., Lee J.H., Kim H.K. Biportal robotic surgery for anterior mediastinal mass. Ann. Cardiothorac. Surg. 2023;12:110–116. doi: 10.21037/acs-2022-urats-24. - DOI - PMC - PubMed

MeSH terms

LinkOut - more resources