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. 2025 May 27;15(1):18479.
doi: 10.1038/s41598-025-02987-9.

Influencing factors affecting health-promoting lifestyles in patients with primary liver cancer: a latent profile analysis

Xuerui Wang #  1 , Jiarong Ding #  2 , Liping Zhou  1 , Qiaomei Fu  3 , Ye Zhang  4 , Yao Lu  5
Affiliations

Influencing factors affecting health-promoting lifestyles in patients with primary liver cancer: a latent profile analysis

Xuerui Wang et al. Sci Rep. .

Abstract

To explore the potential profile categories of health promoting lifestyle in patients with primary liver cancer and analyze the influencing factors of different categories. Primary liver cancer patients who visited a tertiary hospital in Nanjing from October 2021 to May 2023 were selected as the survey subjects. A general information questionnaire and a health-promotion lifestyle scalewere used for data collection. Potential profile analysis was conducted to classify the health-promoting lifestyles of patients with primary liver cancer, and the influencing factors of different categories were explored through univariate analysis and multiple logistic regression analysis. Clinical registration trial number: ChiCTR2400079823 (12/01/2024). A total of 328 questionnaires were collected, of which 324 were valid, resulting in a validity rate of 98.78%.The latent profile analysis indicates that the health promotion lifestyle of primary liver cancer patients can be categorized into three potential profiles: "low health promotion neglect" (n = 128, 39.5%), "moderate health promotion balance" (n = 87, 26.9%), and "high health promotion lone hero" (n = 109, 33.6%). The influencing factors include educational level, per capita monthly income, disease-related economic burden, postoperative duration, work status, sleep disorders, and whether neoadjuvant therapy was administered preoperatively (P < 0.05). Conclusion: There is significant heterogeneity in the health promotion lifestyles of patients with primary liver cancer. Nursing staff should develop targeted health promotion strategies, focusing on improving patients' health behaviors to enhance their quality of life.

Keywords: Analysis of influencing factors; Health literacy; Health promotes lifestyle; Potential profile analysis; Primary liver cancer.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests. Ethical approval: All methods were carried out in accordance with declaration of Helsinki. This study has been approved by the Ethics Committee of the hospital and obtained the clinical registration number of Gulou Hospital: (GLYY:2019-094-01). All subjects have given informed consent and voluntarily participated in the study. Clinical registration trial number: ChiCTR2400079823(12/01/2024).

Figures

Fig. 1
Fig. 1
The characteristic distribution of 3 potential categories of the health promoting lifestyle among primary liver cancer patients.
See this image and copyright information in PMC

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