Multidisciplinary DRG management for rational medication in obstetrics: a cost analysis in Zhejiang Province
- PMID: 40426168
- PMCID: PMC12117813
- DOI: 10.1186/s12913-025-12905-4
Multidisciplinary DRG management for rational medication in obstetrics: a cost analysis in Zhejiang Province
Abstract
Background: Zhejiang Province introduced diagnosis-related group (DRG) payment reform in 2020, covering all hospitalizations to reduce costs and improve services. However, its emphasis on financial indicators and overlooks the evaluation of medical rationality, especially for pregnant women. To bridge this gap, this study developed an obstetric multidisciplinary team (MDT) model in which pharmacists are integrated into prenatal decision-making. This represents a transformation from reactive cost control to proactive medication optimization.
Methods: This study collected DRG data of obstetric patients from a hospital between 2020 and 2024. First, we descripted the overall DRG operational performance and identified OZ13 (Other Pregnancy-Related diseases, with General Complications and Comorbidities) as the target disease groups by the Boston Matrix analysis. Subsequently, we employed Spearman correlation and Kruskal-Wallis H tests to identify key cost drivers. Finally, we applied a generalized linear model with gamma distribution and log-link function to determine key factors influencing medical costs.
Results: After the implementation of the multidisciplinary team management, the Time Consumption Index (TCI) decreased from 1.06 to 0.9 and the Cost Consumption Index (CCI) dropped from 1 to 0.91. Meanwhile, the Case Mix Index (CMI) increased to 0.51. The OZ13 group was selected for follow-up analysis using the Boston Matrix analysis because group exhibited decreased average hospitalization expenditure but an increased Cost Consumption Index. OZ13 group analysis revealed hospitalization costs strongly correlated with pharmaceutical costs (p = 0. 81, P < 0. 01), with significant expenditure differences between 2020 and 2024 (P < 0. 05). Furthermore, the generalized linear model identified several factors influencing hospitalization costs for OZ13 patients, including a history of recurrent miscarriage or IVF status, gestational weeks, parity, age, and length of hospital stay.
Conclusions: The research findings show that early pharmacist involvement in the multidisciplinary team management has positively impacted hospital functioning, including quality, efficiency, and costs. It identifies pharmaceutical costs as the main adjustable expenditure in OZ13 disease group and highlights the necessity of differentiated management for complex cases.
Keywords: Cost analysis; DRG payment reform; Multidisciplinary team; Obstetrics.
© 2025. The Author(s).
Conflict of interest statement
Declarations. Ethics approval and consent to participate: The studies involving human participants are reviewed and approved by the Ethics Committee of Women’s Hospital, Zhejiang University School of Medicine (NO. IRB-20230, 089-R). These studies were conducted in accordance with the Declaration of Helsinki. Despite the waiver for written consent, verbal informed consent was obtained from all participants, as the research involved minimal risk and fully anonymized data. All methods were performed in accordance with the relevant guidelines and regulations. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.
Figures





Similar articles
-
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320. Health Technol Assess. 2001. PMID: 12065068
-
Elective THA for Indications Other Than Osteoarthritis Is Associated With Increased Cost and Resource Use: A Medicare Database Study of 135,194 Claims.Clin Orthop Relat Res. 2024 Jul 1;482(7):1159-1170. doi: 10.1097/CORR.0000000000002922. Epub 2023 Nov 24. Clin Orthop Relat Res. 2024. PMID: 38011034 Free PMC article.
-
Home treatment for mental health problems: a systematic review.Health Technol Assess. 2001;5(15):1-139. doi: 10.3310/hta5150. Health Technol Assess. 2001. PMID: 11532236
-
Maternal and neonatal outcomes of elective induction of labor.Evid Rep Technol Assess (Full Rep). 2009 Mar;(176):1-257. Evid Rep Technol Assess (Full Rep). 2009. PMID: 19408970 Free PMC article.
-
[Volume and health outcomes: evidence from systematic reviews and from evaluation of Italian hospital data].Epidemiol Prev. 2013 Mar-Jun;37(2-3 Suppl 2):1-100. Epidemiol Prev. 2013. PMID: 23851286 Italian.
References
-
- Tan J, Xiong Y, Liu C, et al. A population-based cohort of drug exposures and adverse pregnancy outcomes in China (DEEP): rationale, design, and baseline characteristics. Eur J Epidemiol. 2024;3(4):433–45. - PubMed
-
- Patel A, Sushko K, Mazer-Amirshahi M, et al. Availability of safe and effective therapeutic options to pregnant and lactating individuals following the united States food and drug administration pregnancy and lactation labeling rule. J Pediatr. 2023;259:113342–113342. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous