doi: 10.1083/jcb.73.2.279.
Intramolecular heterogeneity of mitochondrial DNA of Drosophila melanogaster
- PMID: 404300
- PMCID: PMC2109910
- DOI: 10.1083/jcb.73.2.279
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Intramolecular heterogeneity of mitochondrial DNA of Drosophila melanogaster
J Cell Biol.
1977 May.
Abstract
DNA from purified mitochondria of Drosophila melanogaster can be isolated as supercoiled molecules which when nicked have a contour length of 5.9 micron. Partial denaturation mapping shows regional heterogeneity of base composition with one early denaturing region, with a calculated GC content close to zero, extending over 20% of the genome. DNA isolated from unfertilized eggs shows nuclear and mitochondrial DNA in equal proportions; we found no evidence of other cytoplasmic species.
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