Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2025 May 8;17(10):1613.
doi: 10.3390/nu17101613.

Ergogenic Effects of Combined Caffeine Supplementation and Motivational Music on Anaerobic Performance in Female Handball Players: A Randomized Double-Blind Controlled Trial

Affiliations
Randomized Controlled Trial

Ergogenic Effects of Combined Caffeine Supplementation and Motivational Music on Anaerobic Performance in Female Handball Players: A Randomized Double-Blind Controlled Trial

Houda Bougrine et al. Nutrients. .

Abstract

Listening to self-selected motivational music (SSMM) during warm-ups and caffeine (CAF) intake prior to exercise can independently enhance athletic performance among female athletes. Likewise, the potential synergistic effects of these interventions have not yet been thoroughly examined.

Objective: The purpose of the study was to assess the independent and combined effects of SSMM during warm-up and pre-exercise CAF intake on maximal short-duration performance in female athletes.

Methods: Seventeen female handball players (aged 16.7 ± 0.4 years) participated in a randomized, double-blind, crossover study. Each athlete completed four conditions: (i) placebo (PLA) with no interventions, (ii) music and placebo (MUS), (iii) caffeine intake only (CAF), and (iv) a combination of music and caffeine (MUS + CAF). Performance assessments included the countermovement jump (CMJ), modified agility t-test (MAT), repeated-sprint ability (RSA) test (mean and peak sprint performance), and rating of perceived exertion (RPE).

Results: The MUS (p > 0.05; p < 0.01; p < 0.01; p < 0.001, respectively), CAF (all p < 0.001), and MUS + CAF (all p < 0.01) conditions significantly outperformed the PLA condition in CMJ, MAT, RSA mean, and RSA peak measures. No significant differences were observed between the CAF and MUS + CAF conditions; however, the best performances were recorded during MUS + CAF. RPE scores remained consistent across conditions.

Conclusions: Warm-up routines incorporating either SSMM or a moderate dose of CAF (6 mg·kg-1) enhance anaerobic performance in female athletes. While both interventions are effective independently, CAF intake elicits a stronger effect. Although no significant difference was demonstrated for this combination, the concurrent use of SSMM and CAF appears to produce a potential effect, emerging as the most effective strategy for optimizing anaerobic performance.

Keywords: anaerobic performance; caffeine; handball; repeated-sprint ability; self-selected motivational music; warm-up.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Experimental design. PLA: placebo (cellulose), CMJ: countermovement jump, MAT: modified agility t-test, RSA: repeated-sprint ability, RPE: rating of perceived exertion; CAF: 6 mg.kg−1 CAF intake.
Figure 2
Figure 2
Mean ± SD values of the countermovement jump (CMJ) test (A) and modified agility t-test (MAT) (B) recorded under four conditions: PLA, placebo; music, listening to motivational music without CAF intake; CAF, 6 mg.kg−1 CAF intake without listening to motivational music; CAF + music, 6 mg.kg−1 CAF intake with listening to motivational music. a: Significant difference compared to the PLA condition (p < 0.05); b: significant difference compared to the music condition (p < 0.05).
Figure 3
Figure 3
Mean ± SD values of the RSA mean (A) and RSA peak (B) recorded under four conditions: PLA, placebo; music, listening to motivational music without CAF intake; CAF, 6 mg·kg−1 CAF intake without listening to motivational music; CAF + music, 6 mg.kg−1 CAF intake with listening to motivational music. a: Significant difference compared to the PLA condition (p < 0.05); b: significant difference compared to the music condition (p < 0.05).
Figure 4
Figure 4
Mean ± SD values of rating of perceived exertion (RPE) recorded under four conditions: PLA, placebo; Music, listening to motivational music without CAF intake; CAF, 6 mg·kg−1 CAF intake without listening to motivational music; CAF + Music, 6 mg.kg−1 CAF intake with listening to motivational music. a: significant difference compared to the PLA condition (p < 0.05); b: significant difference compared to the Music condition (p < 0.05).

Similar articles

Cited by

References

    1. Filip-Stachnik A., Spieszny M., Stanisz L., Krzysztofik M. Does Caffeine Ingestion Affect the Lower-Body Post-Activation Performance Enhancement in Female Volleyball Players? BMC Sports Sci. Med. Rehabil. 2022;14:93. doi: 10.1186/s13102-022-00488-0. - DOI - PMC - PubMed
    1. Dergaa I., Ben Saad H., El Omri A., Duque J.D.P., Chaabane M., Chamari K. Mental, Physiological and Medical Considerations for Elite Football Players in the Saudi Pro League: A Call for Action. BMJ Open Sport. Exerc. Med. 2023;9:e001789. doi: 10.1136/bmjsem-2023-001789. - DOI - PMC - PubMed
    1. Lu Y., Wang C. Systematic Literature Review on the Immediate Effects of Caffeine on Athletes’ Sports Performance. Preprint. 2025 doi: 10.21203/rs.3.rs-5658525/v1. - DOI
    1. Moscatelli F., Monda A., Messina A., Monda M., Monda V., Villano I., De Maria A., Nicola M., Marsala G., De Stefano M.I., et al. Evaluation of Orexin-A Salivary Levels and Its Correlation with Attention After Non-Invasive Brain Stimulation in Female Volleyball Players. Sports Med.-Open. 2024;10:32. doi: 10.1186/s40798-024-00698-5. - DOI - PMC - PubMed
    1. Vyas A.J.V., Khanvilkar N.P. Role of Sports Psychology in Context to Development of Sports Performance. Int. J. Multidiscip. Res. 2024;6:21849. doi: 10.36948/ijfmr.2024.v06i03.21849. - DOI

Publication types

LinkOut - more resources