Biomarkers to measure the need and the effectiveness of therapeutic supplementation: a critical issue
- PMID: 40435170
- DOI: 10.1515/cclm-2025-0518
Biomarkers to measure the need and the effectiveness of therapeutic supplementation: a critical issue
Keywords: analytical quality; deficiency; harmonization; reproducibility; supplementation; threshold.
References
-
- de Oliveira Andrade, R. Huge reproducibility project fails to validate dozens of biomedical studies. https://www.nature.com/articles/d41586-025-01266-x .
-
- Chandyo, RK, Kvestad, I, Ulak, M, Ranjitkar, S, Hysing, M, Shrestha, M, et al.. The effect of vitamin B12 supplementation during pregnancy on infant growth and development in Nepal: a community-based, double-blind, randomised, placebo-controlled trial. Lancet 2023;401:1508–17. https://doi.org/10.1016/s0140-6736(23)00346-x . - DOI
-
- Upadhyay, RP, Chowdhury, R, Mundra, S, Taneja, S, Jacob, M, Kapil, U, et al.. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Global Health 2025;13:e497–507. https://doi.org/10.1016/s2214-109x(24)00559-x . - DOI
-
- Abdelwahab, OA, Abdelaziz, A, Diab, S, Khazragy, A, Elboraay, T, Fayad, T, et al.. Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: a systematic review and network meta-analysis. Ir J Med Sci 2024;193:1621–39. https://doi.org/10.1007/s11845-023-03602-4 . - DOI
-
- Finkelstein, JL, Fothergill, A, Venkatramanan, S, Layden, AJ, Williams, JL, Crider, KS, et al.. Vitamin B12 supplementation during pregnancy for maternal and child health outcomes. Cochrane Database Syst Rev 2024;1:CD013823. https://doi.org/10.1002/14651858.CD013823.pub2 . - DOI
Publication types
LinkOut - more resources
Full Text Sources