Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Jul 11:60:127309.
doi: 10.1016/j.vaccine.2025.127309. Epub 2025 May 27.

Co-administration of vaccines in pregnancy: unique challenges and knowledge gaps

Bahaa Abu-Raya  1 , Michelle L Giles  2 , Tobias Kollmann  3
Affiliations
Free article
Review

Co-administration of vaccines in pregnancy: unique challenges and knowledge gaps

Bahaa Abu-Raya et al. Vaccine. .
Free article

Abstract

Vaccination in pregnancy directly protects the mother and can prevent serious infections in early life. There are an increasing number of vaccines that are recommended during pregnancy and deployed in a growing number of countries. However, most recommendations for administration of these vaccines in pregnancy are based on studies that investigate one vaccine at a time. Largely lacking are data on the impact of co-administration including spacing and timing of the multiple vaccines during pregnancy on safety, efficacy and immunogenicity. We here place what is known into the context co-administration of vaccines with focus on the mother as well as the infant.

Keywords: Co-administration; Pertussis; Pregnancy; RSV; Vaccination.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: BA received honoraria for participation in live meetings from Sanofi Pasteur France and Canada related to pertussis and RSV. BA received nominal payment as a reviewer for ELSEVIER and as a member of a data and safety monitoring board for a study conducted by Chulalongkorn University (Bangkok, Thailand). BA is co-investigator on studies funded by GSK, Pfizer, Merck, Moderna, Vaccitech and Inventprise. All funds have been paid to his institute, and he has not received any personal payments. TK and MG do not have any conflict of interest to declare.

LinkOut - more resources