Metabolic Rewiring in Calcific Aortic Valve Disease: It Goes Beyond Immunometabolism

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Editorial

Adrien Lupieri. Arterioscler Thromb Vasc Biol. 2025 Jul.

Free article

. 2025 Jul;45(7):1041-1043.

doi: 10.1161/ATVBAHA.125.322959. Epub 2025 May 29.

¹ Division of Cardiovascular Medicine, Center for Excellence in Vascular Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

No abstract available

Keywords: Editorials; aortic valve disease; calcification; inflammation; metabolism.

Conflict of interest statement

None.

Inflammation via JAK-STAT/HIF-1α Drives Metabolic Changes in Pentose Phosphate Pathway and Glycolysis That Support Aortic Valve Cell Calcification.
Sánchez-Bayuela T, Peral-Rodrigo M, Parra-Izquierdo I, López J, Gómez C, Montero O, Pérez-Riesgo E, San Román JA, Butcher JT, Sánchez Crespo M, García-Rodríguez C. Sánchez-Bayuela T, et al. Arterioscler Thromb Vasc Biol. 2025 Jul;45(7):e232-e249. doi: 10.1161/ATVBAHA.124.322375. Epub 2025 May 1. Arterioscler Thromb Vasc Biol. 2025. PMID: 40308196