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Case Reports
. 2025 Jun;31(6):1227-1230.
doi: 10.3201/eid3106.241955.

Skin Infections Caused by Panton-Valentine Leukocidin and Methicillin-Susceptible Staphylococcus aureus in Child, Japan

Kensuke Shoji, Kazue Yoshida, Marie Takenouchi, Junzo Hisatsune, Shoko Kutsuno, Chika Arai, Kanako Masuda, Motoyuki Sugai, Takashi Ishikawa, Toshinao Kawai, Kazuhiro Uda, Isao Miyairi
Case Reports

Skin Infections Caused by Panton-Valentine Leukocidin and Methicillin-Susceptible Staphylococcus aureus in Child, Japan

Kensuke Shoji et al. Emerg Infect Dis. 2025 Jun.

Abstract

We describe a pediatric case of recurrent skin infections caused by a Panton-Valentine leukocidin and exfoliative toxin E double-positive methicillin-susceptible Staphylococcus aureus clonal complex 188 clone. Most of the patient's family members were infected with the same strain, and intrafamilial transmission was strongly suspected. Decolonization procedures were not effective.

Keywords: Japan; MSSA; Panton-Valentine leucocidin; Staphylococcus; methicillin-susceptible Staphylococcus aureus; pediatrics; skin infections.

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Figures

Figure 1
Figure 1
Multiple furuncles (furunculosis) on forearm (A) and thigh (B) of child experiencing recurrent skin infections caused by Panton-Valentine leukocidin and exfoliative toxin E double-positive methicillin-susceptible Staphylococcus aureus clonal complex 188 clone, Japan.
Figure 2
Figure 2
Timeline of symptoms and treatment of child experiencing recurrent skin infections caused by Panton-Valentine leukocidin and exfoliative toxin E double-positive methicillin-susceptible Staphylococcus aureus clonal complex 188 clone, Japan.
See this image and copyright information in PMC

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