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. 2025 Jul 1;11(7):791-794.
doi: 10.1001/jamaoncol.2025.1199.

Acupuncture for Nocturia in Survivors of Prostate Cancer: The NOCTURNAL Randomized Clinical Trial

Kevin T Liou  1 , Sigrid Carlsson  2   3   4   5 , Divya Ajay  2 , Jaspreet S Sandhu  2 , Yuelin Li  3   6 , Q Susan Li  1 , Felix Cheung  2 , Kamy Chong  1 , Allison Booher  1 , Katherine Han  1 , Kaitlin Lampson  1 , Christian Nelson  6 , Michael J Morris  1 , Vincent P Laudone  2 , Jun J Mao  1
Affiliations

Acupuncture for Nocturia in Survivors of Prostate Cancer: The NOCTURNAL Randomized Clinical Trial

Kevin T Liou et al. JAMA Oncol. .
No abstract available

Plain language summary

This pilot randomized clinical trial evaluates acupuncture relative to usual care for the treatment of nocturia in survivors of prostate cancer.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Liou reported grants from Chanel Endowment to Fund Survivorship Research, grants from the National Cancer Institute (NCI) (K08CA266927), and grants from NCI (P30CA008748) during the conduct of the study. Dr Carlsson reported personal fees from Ipsen, Astellas, and Prostatype Genomics, and grants from National Institutes of Health (NIH)/NCI (P30CA008748) outside the submitted work. Dr Ajay reported grants from Chanel Endowment to Fund Survivorship Research, NCI K08 award (5K08CA266927), and grants from NCI core grant (P30CA008748) during the conduct of the study. Dr Booher reported grants from NCI core grant (P30CA008748) during the conduct of the study. Dr Morris reported personal fees from Lantheus, Convergent Therapeutics, Clarity Pharmaceuticals, Blue Earth Diagnostics, Z-Alpha, Ambrx, Flare Therapeutics, Curium, Transtherabio, BMS/Celgene, Arvinas, Exelexis, and Amgen outside the submitted work; and MSK receives research royalties from Telix. Also institutional research funds for the conduct of clinical trials from Janssen, Novartis, Astellas, AstraZeneca, and Fusion. Dr Mao reported grants from NIH/NCI Cancer Center P30 (CA008748) made to Memorial Sloan Kettering Cancer Center during the conduct of the study; grants from Tibet CheeZheng Tibetan Medicine Co Ltd Made to institution and grants from Zhongke Health International LLC Made to institution outside the submitted work; and Co-presidency of the Society for Acupuncture Research (unpaid). No other disclosures were reported.

References

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    1. Barry MJ, Williford WO, Chang Y, et al. Benign prostatic hyperplasia specific health status measures in clinical research: how much change in the American Urological Association symptom index and the benign prostatic hyperplasia impact index is perceptible to patients? J Urol. 1995;154(5):1770-1774. doi: 10.1016/S0022-5347(01)66780-6 - DOI - PubMed
    1. Sakalis VI, Karavitakis M, Bedretdinova D, et al. Medical treatment of nocturia in men with lower urinary tract symptoms: systematic review by the European Association of Urology Guidelines Panel for Male Lower Urinary Tract Symptoms. Eur Urol. 2017;72(5):757-769. doi: 10.1016/j.eururo.2017.06.010 - DOI - PubMed

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