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. 2025 Aug:209:110962.
doi: 10.1016/j.radonc.2025.110962. Epub 2025 May 27.

An additional peril of pathologic complete response

Orit Kaidar-Person  1 , Philip Poortmans  2 , Icro Meattini  3 , Trine Tramm  4
Affiliations
Free article

An additional peril of pathologic complete response

Orit Kaidar-Person et al. Radiother Oncol. 2025 Aug.
Free article

Abstract

Pathological complete response (pCR) has been shown to predict long-term outcomes in breast cancer patients undergoing primary systemic therapy in aggressive early breast cancer. Herein we discuss the caveats of determining pCR, and data needed to tailor breast cancer radiation after pCR.

Keywords: Breast cancer; Neoadjuvant; Pathological complete response; Primary systemic therapy; Radiation.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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