Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jun 16;14(6):piaf049.
doi: 10.1093/jpids/piaf049.

Acute Gastroenteritis Among Household Contacts of Children with Severe Norovirus Gastroenteritis, United States, 2011-2016

Mary C Moran  1 , Mary E Wikswo  1 , Rangaraj Selvarangan  2 , Christopher J Harrison  2 , Leila C Sahni  3   4 , Julie A Boom  3   4 , Natasha Halasa  5 , Laura S Stewart  5 , Daniel C Payne  6   7 , Mary Allen Staat  6   7 , Geoffrey A Weinberg  8   9 , Peter G Szilagyi  8   9   10   11 , Janet A Englund  12   13 , Eileen J Klein  12   13 , Jan Vinjé  1 , Umesh D Parashar  1 , Jacqueline E Tate  1 , Sara A Mirza  1
Affiliations

Acute Gastroenteritis Among Household Contacts of Children with Severe Norovirus Gastroenteritis, United States, 2011-2016

Mary C Moran et al. J Pediatric Infect Dis Soc. .

Abstract

Norovirus-associated acute gastroenteritis (AGE) in children <11 years resulted in substantial AGE illness among household contacts (HHCs). Vomiting (≥5 episodes in 24 hours) was the greatest risk factor (aOR, 2.85, [95% CI, 1.91-4.26]) for AGE symptoms among HHCs of norovirus-positive index cases. HHCs age 0-4 years had the highest attack rates (22%).

Keywords: Norovirus; acute gastroenteritis; household transmission.

Plain language summary

Households of children with norovirus-positive acute gastroenteritis (AGE) have more AGE illness among household contacts than households of children with norovirus-negative AGE. Children <5 years are important contributors to AGE spread and frequent vomiting episodes increase the risk of transmission.

PubMed Disclaimer

MeSH terms