Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Apr 29;17(4):e83206.
doi: 10.7759/cureus.83206. eCollection 2025 Apr.

Use of Dexmedetomidine as an Adjuvant in Spinal Anesthesia in Patients With Femoral Fracture Affected by Moderate Aortic Stenosis: A Case Series

Affiliations
Case Reports

Use of Dexmedetomidine as an Adjuvant in Spinal Anesthesia in Patients With Femoral Fracture Affected by Moderate Aortic Stenosis: A Case Series

Stefano Barbaro et al. Cureus. .

Abstract

The anaesthesiological management of femoral fracture in the frail patient still represents a challenge for the anaesthetist and his team. For decades, the most frequently used anaesthesiological approach in these cases has been spinal anaesthesia. In recent years, the progression of pharmacology and anaesthesiological techniques has meant that this technique can be adopted in situations where general anaesthesia was previously preferred, particularly in clinical scenarios requiring less haemodynamic impact, such as in patients with aortic valve stenosis. In this case series, we consider how adjuvant spinal anaesthesia with dexmedetomidine ensures adequate intra- and post-operative analgesia and haemodynamic stability in patients with moderate aortic valvular stenosis. Specifically, we used the Visual Analogue Scale (VAS) score to evaluate pain, both intraoperatively and postoperatively at 6, 12, and 24 hours.

Keywords: `anesthesia; adjuvant drugs; anesthesia spinal; critical aortic stenosis; elderly population.

PubMed Disclaimer

Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

References

    1. Effects of successful, uncomplicated valve replacement on ventricular hypertrophy, volume, and performance in aortic stenosis and in aortic incompetence. Pantely G, Morton M, Rahimtoola SH. https://pubmed.ncbi.nlm.nih.gov/147370/ J Thorac Cardiovasc Surg. 1978;75:383–391. - PubMed
    1. Wall stress and patterns of hypertrophy in the human left ventricle. Grossman W, Jones D, McLaurin LP. J Clin Invest. 1975;56:56–64. - PMC - PubMed
    1. Central regional anaesthesia in patients with aortic stenosis-a systematic review. Johansson S, Lind MN. https://pubmed.ncbi.nlm.nih.gov/28874243/ Dan Med J. 2017;64:5407. - PubMed
    1. Aortic stenosis in the elderly: disease prevalence and number of candidates for transcatheter aortic valve replacement: a meta-analysis and modeling study. Osnabrugge RL, Mylotte D, Head SJ, et al. J Am Coll Cardiol. 2013;62:1002–1012. - PubMed
    1. Prognostic value of left ventricular myocardial work indices in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Wu HW, Fortuni F, Butcher SC, et al. Eur Heart J Cardiovasc Imaging. 2023;24:1682–1689. - PMC - PubMed

Publication types

LinkOut - more resources