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. 2025 Jul;91 Suppl 1(Suppl 1):101614.
doi: 10.1016/j.bjorl.2025.101614. Epub 2025 May 29.

Evaluation of clinical outcomes after partial horizontal laryngectomy

Daniel Abreu Rocha  1 , Gustavo Fernandes de Alvarenga  2 , Daniel Marin Ramos  3 , Leandro Luongo de Matos  3 , Rogerio Aparecido Dedivitis  2 , Marco Aurélio Vamondes Kulcsar  3 , Claudio Roberto Cernea  2
Affiliations

Evaluation of clinical outcomes after partial horizontal laryngectomy

Daniel Abreu Rocha et al. Braz J Otorhinolaryngol. 2025 Jul.

Abstract

Objective: Evaluate the oncological and functional outcomes of patients submitted to HPL for the treatment of LSCC.

Methods: A retrospective descriptive study of patients submitted to HPL, performed at a cancer referral center, between January 2011 and December 2017.

Results: We evaluated 37 patients. The major pathological staging of the primary tumor was pT3 (35.1%), followed by pT2 (32.4%). Five patients required adjuvant radiotherapy; 62.2% of the patients were decannulated by the end of the treatment; 10.8% weren't decannulated; 8.1% underwent a retracheostomy, and 18.9% had total laryngectomy. From the patients submitted to total laryngectomy, 3 cases were due to rehabilitation failure, 2 due to recurrence and 2 cases due to postoperative suture dehiscence. About 89% of the patients resumed oral feeding following the procedure; 86.4% didn't present disease recurrence; 31 patients survived without disease; 3 died from disease-related causes, and 3 from unrelated causes.

Conclusion: HPL is an alternative procedure to total laryngectomy, presenting adequate rates of local control and overall survival while also maintaining laryngeal function. The main challenge to HPL remains achieving an ideal selection of patients.

Level of evidence: Level IV.

Keywords: Laryngeal neoplasms; Laryngectomy; Larynx; Open partial laryngectomy.

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Conflict of interest statement

Declaration of competing interest The authors declare no conflicts of interest.

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