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Comparative Study
. 2025 May 30;25(1):1995.
doi: 10.1186/s12889-025-23114-3.

Temporal trends in HIV prevention service access and use among female sex workers (FSW) in Mozambique: a comparative analysis 2011-2019

Affiliations
Comparative Study

Temporal trends in HIV prevention service access and use among female sex workers (FSW) in Mozambique: a comparative analysis 2011-2019

Samuel Nuvunga et al. BMC Public Health. .

Abstract

Background: Female sex workers (FSWs) remain disproportionately affected by HIV due to a combination of structural, social, and behavioral factors, including stigma, limited access to health services, gender-based violence, and legal barriers. In Mozambique, where sex work is informal and highly marginalized, monitoring trends in service uptake is essential to guide responsive and equitable HIV interventions. This study analyzes changes in access to and use of HIV prevention services among FSWs between 2011 and 2019.

Methods: We conducted a secondary analysis of cross-sectional bio-behavioral survey (BBS) data collected among FSWs in 2011 and 2019 in three Mozambican urban centers. Standardized questionnaires were used to collect behavioral and biological data, including indicators of HIV prevention service access. Participants were recruited using Respondent-Driven Sampling (RDS). Logistic regression was applied to assess time trends and identify factors associated with service uptake.

Results: A total of 1,240 FSWs participants were recruited in 2011 and 1,530 in 2019. Between 2011 and 2019, there was a significant increase in HIV prevalence (from 11.9 to 24.5%). The proportion of participants accessing HIV prevention services more than doubled (from 21.4 to 52.3%), alongside marked improvements in HIV testing uptake (68.0-83.1%) and consistent condom use with clients (74.1-86.3%). Multivariate analysis showed that age ≥ 25, moderate HIV risk perception, and experiences of sexual violence were positively associated with access to prevention services in 2019. In contrast, alcohol use and physical assault were negatively associated with service use. Determinants of access shifted over time; for example, while secondary education was positively associated with service access in 2011, it was negatively associated in 2019.

Conclusion: There has been substantial progress in access to and use of HIV prevention services among FSWs in Mozambique over the past decade. Nonetheless, the rising HIV prevalence and persistent disparities related to age, education, economic vulnerability, and exposure to violence signal the need for more comprehensive, context-specific, and equity-focused strategies. Reinforcing peer-led outreach, integrating gender-based violence response, and addressing risk misperception are critical to strengthening Mozambique's HIV prevention continuum for this key population.

Keywords: Female sex workers; HIV; Health services accessibility; Key populations; Mozambique; Prevention.

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Conflict of interest statement

Declarations. Ethical approval and consent to participate: All eligible participants in both BBS rounds (2011 and 2019) provided written informed consent prior to participation. The consent process was designed to allow participants to provide separate consent for different components of the survey, including the option to decline HIV testing while still completing the behavioral questionnaire. The two BBS surveys received ethical approval from the National Bioethics Committee for Health (CNBS) in Mozambique and the INS Institutional Bioethics Committee for Health (CIBS-INS). Written informed consent was obtained from all participants prior to enrolment in the surveys. Additionally, the secondary analysis protocol underlying this manuscript was reviewed and approved by the Institutional Bioethics Committee for Health of the Faculty of Medicine and Maputo Central Hospital (CIBS FM&HCM/086/2021, Version 1.4, April 2022). The INS granted formal authorization for the use of the BBS-FSW database. Consent to publish: Not applicable. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Proportion of FSWs with access to health services for HIV/AIDS prevention in Mozambique, 2011 and 2019. The percentages are weighted and were computed using weighted and were computed using the Gile’s sequential sampling (SS)
Fig. 2
Fig. 2
Proportion of FSWs who used health services for HIV/AIDS prevention among FSWs in Mozambique, 2011 and 2019. The percentages are weighted and were computed using weighted and were computed using the Gile’s sequential sampling (SS)

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