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. 2025:2885:683-691.
doi: 10.1007/978-1-0716-4306-8_33.

Raman Microscopy and Bone

Richard M Aspden  1
Affiliations

Raman Microscopy and Bone

Richard M Aspden. Methods Mol Biol. 2025.

Abstract

Raman microscopy is a non-destructive technique requiring minimal sample preparation that can be used to measure the chemical properties of the mineral and collagen parts of bone simultaneously. Modern Raman instruments contain the necessary components and software to acquire the standard information required in most bone studies. The spatial resolution of the technique is about a micron. As it is non-destructive and small samples can be used, it forms a useful part of a bone characterization toolbox.

Keywords: Bone chemistry; Material properties; Raman; Spectroscopy.

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