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. 1985 Nov;135(5):3354-9.

Antibodies to the alpha-subunit of insulin receptor from eggs of immunized hens

C S Song, J H Yu, D H Bai, P Y Hester, K H Kim
  • PMID: 4045194

Antibodies to the alpha-subunit of insulin receptor from eggs of immunized hens

C S Song et al. J Immunol. 1985 Nov.

Abstract

Simple methods for the generation, purification, and assay of antibodies to the alpha-subunit of insulin receptor from eggs of immunized hens have been described. Chicken antibodies against the alpha-subunit inhibit insulin binding to the receptor and stimulate glucose oxidation as well as autophosphorylation of the beta-subunit. Thus the properties of chicken antibodies are very similar to those of antibodies found in human autoimmune diseases and different from rabbit antibodies obtained against the same antigen.

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