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. 2025 May 16:12:1559543.
doi: 10.3389/fmed.2025.1559543. eCollection 2025.

A bibliometric analysis of the frontiers and hotspots in chronic endometritis

Yunfang Luo  1 , Qin Huang  2 , Xing Li  2 , Chaogang Yang  3   4   5 , Jinli Ding  1
Affiliations

A bibliometric analysis of the frontiers and hotspots in chronic endometritis

Yunfang Luo et al. Front Med (Lausanne). .

Abstract

Background: Chronic endometritis (CE) is an inflammatory condition characterized by endometrial plasmacyte infiltration. The diagnosis and treatment of CE have attracted more and more attention. This article aimed to analyze the relevant keywords, development trends, and research hotspots of CE, which can provide a direction for future research.

Materials and methods: The relevant articles on CE were retrieved from the Web of Science Core Collection. VOSviewer and CiteSpase were applied to analyze publication years, countries, institutions, journals, authors, citation and co-citation, co-occurrence and citation burst of keywords.

Results: A total of 373 publications on CE were retrieved. Annual publication of articles about CE grew rapidly, and 2022 had the biggest outputs (50). USA contributed the most publications (87), and the University of Bari Aldo Moro had the highest number of articles in this field (27). The journal with the highest cited count and most publications was Fertility and Sterility (30). The main disciplines concerning the research on CE were Obstetrics Gynecology (141, 38.11%) and Reproductive Biology (126, 34.05%). Ettore Cicinelli, Kotaro Kitaya, and Dominique De Ziegler were the top three authors in publications. Except for CE and endometritis, the five most common keywords were infertility, hysteroscopy, plasma cell, recurrent implantation failure, and CD138. Pregnancy loss and recurrent miscarriage are currently within the burst period and might be the persistent research heated topics in this field.

Conclusion: This study is useful for researchers to quickly grasp the current situation of CE research and enlighten researchers to explore new problems in CE.

Keywords: CD138; bibliometric analysis; chronic endometritis; infertility; pregnancy loss.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
The mind map of the collection and origin of the data.
Figure 2
Figure 2
The publications and citations per year regarding chronic endometritis. (A) publications; (B) citations.
Figure 3
Figure 3
Countries contribution on chronic endometritis. (A) Countries contribution to the publications on chronic endometritis based on CiteSpace. (B) Network map of co-authorship between countries with more than five publications based on VOSviewer.
Figure 4
Figure 4
Network map of co-authorship between institutions with more than five publications.
Figure 5
Figure 5
Network map of co-citation of the cited journals with more than 20 citations.
Figure 6
Figure 6
Co-authorship and cooperation between authors on chronic endometritis. (A) Network map of co-authorship between authors who published more than 4 publications based on VOSviewer. (B) Authors cooperation and their contribution to the publication based on CiteSpace.
Figure 7
Figure 7
The distribution of keywords based on CiteSpace.
Figure 8
Figure 8
Network visualization of keywords. (A) Network visualization of keywords occur more than five times in research on chronic endometritis based on VOSviewer. (B) Network visualization of keywords occur more than five times with timeline based on VOSviewer.
Figure 9
Figure 9
The cluster and timeline of keywords on chronic endometritis. (A) The cluster of keywords based on CiteSpace. (B) The timeline of keywords according to the cluster.
Figure 10
Figure 10
Top 20 keywords with the strongest citation bursts based on CiteSpace.
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References

    1. Michels TC. Chronic endometritis. Am Fam Physician. (1995) 52:217–22. - PubMed
    1. Haggerty CL, Ness RB, Amortegui A, Hendrix SL, Hillier SL, Holley RL, et al. . Endometritis does not predict reproductive morbidity after pelvic inflammatory disease. Am J Obstet Gynecol. (2003) 188:141–8. 10.1067/mob.2003.87 - DOI - PubMed
    1. Kiviat NB, Wolnerhanssen P, Eschenbach DA, Wasserheit JN, Paavonen JA, Bell TA, et al. . Endometrial histopathology in patients with culture-proved upper genital-tract infection and laparoscopically diagnosed acute salpingitis. Am J Surg Pathol. (1990) 14:167–75. 10.1097/00000478-199002000-00008 - DOI - PubMed
    1. Cicinelli E, Matteo M, Tinelli R, Pinto V, Marinaccio M, Indraccolo U, et al. . Chronic endometritis due to common bacteria is prevalent in women with recurrent miscarriage as confirmed by improved pregnancy outcome after antibiotic treatment. Reprod Sci. (2014) 21:640–7. 10.1177/1933719113508817 - DOI - PMC - PubMed
    1. Bashiri A, Halper KI, Orvieto R. Recurrent implantation failure-update overview on etiology, diagnosis, treatment and future directions. Reprod Biol Endocrin. (2018) 16:121. 10.1186/s12958-018-0414-2 - DOI - PMC - PubMed

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