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. 1985 Oct:66 ( Pt 10):2271-7.
doi: 10.1099/0022-1317-66-10-2271.

Mutagen-directed attenuation of Rift Valley fever virus as a method for vaccine development

H Caplen, C J Peters, D H Bishop

Mutagen-directed attenuation of Rift Valley fever virus as a method for vaccine development

H Caplen et al. J Gen Virol. 1985 Oct.

Abstract

Serial mutagenesis with 5-fluorouracil has been employed to derive an attenuated strain of Rift Valley fever virus for use as a live virus vaccine.

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