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. 2025 Jun 2.
doi: 10.1007/s40615-025-02498-3. Online ahead of print.

Neighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis

Brittany L Lane  1 , Eugenia F Millender  2   3   4 , Rachel M Harris  2   3 , Alexandra L Nowak  5 , Nia Josiah  6 , Casey D Xavier Hall  2   3 , Faith Pfeiffer  2 , Frank Y Wong  2   3 , Cindy A Crusto  7 , Stephanie Potts-Thompson  4 , Laura Prescott  4 , Jacquelyn Y Taylor  4
Affiliations

Neighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis

Brittany L Lane et al. J Racial Ethn Health Disparities. .

Abstract

Background: Systemic inequities lead to socioeconomic disparities and increased exposure to neighborhood deprivation among African American women, which in turn may have impacts on mental health. This study examined the individual and cumulative effects of neighborhood deprivation and experiences of trauma on depression among young African American mothers.

Methods: We conducted a longitudinal study using data from the Intergenerational Impact of Genetic and Psychological Factors on Blood Pressure (InterGEN) study. We analyzed demographic and psychological data of 248 participants in Southwest and Central Connecticut, employing descriptive statistics, latent class analysis, and regression analysis to predict depressive symptoms.

Results: In unadjusted models, high potentially traumatic event (PTE) exposure, avoidance coping, and stress were statistically significant predictors of depressive symptoms across all time points. Once adjusted, avoidance coping and stress remained statistically significant at baseline; neighborhood deprivation, mid-level PTE, and stress remained statistically significant at T2; and only stress remained statistically significant at T3.

Conclusions: There is a critical need for a comprehensive approach to address systemic issues rooted in racism and strengthen community resilience to improve mental health among young African American mothers, their families, and communities. Interventions that build on existing community strengths, provide psychological support, and enhance individual coping skills may be effective in fostering resilience and improving mental health.

Keywords: African American; Depression; Neighborhood deprivation; Stress; Trauma.

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Conflict of interest statement

Declarations. Ethics Approval: The InterGEN study received approval from Yale University’s Institutional Review Board. Consent to Participate: Informed consent was obtained from all participants in the study. Competing interests: The authors declare no competing interests.

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