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. 1977 Mar;22(2):194-7.

The effects of IgG2 and of antigen concentration on prozoning in the complement fixation test for bovine brucellosis

D J McNaught, R J Chappel, G S Allan, J A Bourke, B A Rogerson
  • PMID: 404679

The effects of IgG2 and of antigen concentration on prozoning in the complement fixation test for bovine brucellosis

D J McNaught et al. Res Vet Sci. 1977 Mar.

Abstract

Addition of Brucella-specific IgG2 to solutions of Brucella-specific IgG1 initially induced prozoning and at higher concentrations prevented all reaction in the complement fixation test (CFT) for bovine brucellosis. Some infected cattle may be diagnosed as brucellosis-free due to a high ratio of specific IgG2 to IgG1. Increasing the concentration of antigen in the CFT reduced the tendency to prozone.

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