. 2025 Apr 13;4(3):e70028.

doi: 10.1002/imt2.70028. eCollection 2025 Jun.

Enhancing human gut health: Global innovations in dysbiosis management

Reda El Boukhari¹, Maima Matin², Latifa Bouissane³, Michał Ławiński^{2

4}, Oleh Lushchak^{5

6}, Rajeev K Singla^{7

8}, Michel-Edwar Mickael², Jordi Mayneris-Perxachs^{9

10

11}, Maria Eleni Grafakou¹², Shuhua Xu^{13

14}, Bowen Liu¹⁵, Jiayi Guan¹⁶, Andrzej Półtorak¹⁷, Arkadiusz Szpicer¹⁷, Agnieszka Wierzbicka^{2

17}, Nikolay T Tzvetkov¹⁸, Maciej Banach^{19

20

21

22}, Jarosław Olav Horbańczuk², Artur Jóźwik², Marco Cascella²³, Bairong Shen^{24

25}, Vasil Radoslavov Pirgozliev²⁶, Dongdong Wang^{27

28}, Olena Litvinova^{29

30}, Olga Adamska³¹, Agnieszka Kamińska³¹, Marcin Łapiński³², Artur Stolarczyk³², Ioana Berindan-Neagoe³³, Luigi Milella³⁴, Andy Wai Kan Yeung³⁵, Prashanth Suravajhala^{36

37}, Anupam Bishayee³⁸, Ronan Lordan³⁹, Laszlo Barna Iantovics⁴⁰, Ricardo Lagoa^{41

42}, Monika Michalczuk⁴³, Jivko Stoyanov^{44

45}, A Douglas Kinghorn⁴⁶, Banaz Jalil⁴⁷, Wolfram Weckwerth^{48

49}, Bey Hing Goh^{50

51

52}, Meng-Yao Li^{53

54}, Gyaneshwer Chaubey⁵⁵, Gian Luigi Russo⁵⁶, Sara Frazzini⁵⁷, Luciana Rossi⁵⁷, Maurizio Battino^{58

59

60}, Wei Jia⁶¹, Qi Su^{62

63}, Xiaoqiang Ma⁶⁴, Judith M Rollinger⁶⁵, Simon K-M R Rittmann⁶⁶, Helen Sheridan^{67

68}, John J Walsh⁶⁷, Gérard Lizard⁶⁸, Tomasz M Karpiński⁶⁹, Ana Sanches Silva^{70

71}, Jakub Piwowarski⁷², Liwei Xie^{73

74}, Tai-Ping Fan⁷⁴, Francesca Giampieri^{58

59

75

76}, Adil El Midaoui^{77

78}, Ka-Hing Wong^{79

80}, Ren-You Gan^{79

80}, Ahmed Fatimi¹, Atanas G Atanasov^{2

30

81}

Affiliations

¹ Chemical Science and Engineering Research Team (ERSIC), Department of Chemistry, Polydisciplinary Faculty of Beni Mellal (FPBM) Sultan Moulay Slimane University (USMS) Beni Mellal Morocco.
² Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences Jastrzębiec Poland.
³ Molecular Chemistry, Materials and Catalysis Laboratory, Faculty of Sciences and Technologies Sultan Moulay Slimane University Beni Mellal Morocco.
⁴ Department of General, Gastroenterologic and Oncologic Surgery Medical University of Warsaw Warsaw Poland.
⁵ Department of Biochemistry and Biotechnology Vasyl Stefanyk Precarpathian National University Ivano-Frankivsk Ukraine.
⁶ Research and Development University Ivano-Frankivsk Ukraine.
⁷ Department of Pharmacy and Institutes for Systems Genetics, Center for High Altitude Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital Sichuan University Chengdu Sichuan China.
⁸ School of Pharmaceutical Sciences Lovely Professional University Phagwara Punjab India.
⁹ Department of Diabetes, Endocrinology and Nutrition Dr. Josep Trueta University Hospital Girona Spain.
¹⁰ CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) Madrid Spain.
¹¹ Integrative Systems Medicine and Biology Group, Girona Biomedical Research Institute (IDIBGI-CERCA) Parc Hospitalari Martí i Julià Salt Spain.
¹² Chair of Pharmaceutical Biology, Faculty of Pharmacy and Chemistry University of Regensburg Germany.
¹³ Center for Evolutionary Biology, School of Life Sciences Fudan University Shanghai China.
¹⁴ Human Phenome Institute, Zhangjiang Fudan International Innovation Center Fudan University Shanghai China.
¹⁵ School of Agriculture Yunnan University Kunming China.
¹⁶ Henan Institute of Medical and Pharmaceutical Sciences Zhengzhou University Zhengzhou China.
¹⁷ Department of Technique and Food Development, Institute of Human Nutrition Sciences Warsaw University of Life Sciences Warsaw Poland.
¹⁸ Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology "Roumen Tsanev" Bulgarian Academy of Sciences Sofia Bulgaria.
¹⁹ Faculty of Medicine The John Paul II Catholic University of Lublin (KUL) Lublin Poland.
²⁰ Department of Cardiology and Adult Congenital Heart Diseases Polish Mother's Memorial Hospital Research Institute (PMMHRI) Lodz Poland.
²¹ Department of Preventive Cardiology and Lipidology Medical University of Lodz (MUL) Lodz Poland.
²² Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore Maryland USA.
²³ Anesthesia and Pain Medicine, Department of Medicine, Surgery and Dentistry "Scuola MedicaSalernitana" University of Salerno Baronissi Italy.
²⁴ Department of Critical Care Medicine and Institutes for Systems Genetics Frontiers Science Center for Disease-Related Molecular Network, West China Hospital,Sichuan University Chengdu Sichuan China.
²⁵ Center for High Altitude Medicine, West China Hospital Sichuan University Chengdu Sichuan China.
²⁶ National Institute of Poultry Husbandry Harper Adams University Newport UK.
²⁷ Centre for Metabolism, Obesity and Diabetes Research McMaster University Hamilton Ontario Canada.
²⁸ Division of Endocrinology and Metabolism, Department of Medicine McMaster University Hamilton Ontario Canada.
²⁹ National University of Pharmacy of the Ministry of Health of Ukraine Kharkiv Ukraine.
³⁰ Ludwig Boltzmann Institute Digital Health and Patient Safety Medical University of Vienna Vienna Austria.
³¹ Faculty of Medicine Collegium Medicum Cardinal Stefan Wyszyński University in Warsaw Warsaw Poland.
³² Orthopaedic and Rehabilitation Department Medical University of Warsaw Warsaw Poland.
³³ Department of Genomics MEDFUTURE - Institute for Biomedical Research"Iuliu Hațieganu" University of Medicine and Pharmacy No. 23 Cluj-Napoca Romania.
³⁴ Department of Health Sciences University of Basilicata Potenza Italy.
³⁵ Oral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry The University of Hong Kong Pokfulam Hong Kong SAR.
³⁶ Amrita School of Biotechnology Amrita Viswa Vidyapeetham Clappana Kerala India.
³⁷ Department of Biosciences Manipal University Jaipur, Dehmi Kala Jaipur Rajasthan India.
³⁸ Department of Pharmacology College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine Bradenton Florida USA.
³⁹ The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.
⁴⁰ Department of Electrical Engineering and Information Technology George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures Targu Mures Romania.
⁴¹ ESTG-Polytechnic Institute of Leiria Morro do Lena-Alto do Vieiro Leiria Portugal.
⁴² LSRE-LCM-Associate Laboratory in Chemical Engineering University of Porto Porto Portugal.
⁴³ Department of Animal Breeding, Institute of Animal Sciences Warsaw University of Life Sciences - SGGW Warsaw Poland.
⁴⁴ Swiss Paraplegic Research Nottwil Switzerland.
⁴⁵ Institute of Social and Preventive Medicine (ISPM) University of Bern Bern Switzerland.
⁴⁶ College of Pharmacy Ohio State University Columbus Ohio USA.
⁴⁷ Pharmacognosy and Phytotherapy UCL School of Pharmacy London UK.
⁴⁸ Molecular Systems Biology Lab (MOSYS), Department of Functional and Evolutionary Ecology University of Vienna Vienna Austria.
⁴⁹ Vienna Metabolomics Center (VIME) University of Vienna Vienna Austria.
⁵⁰ Sunway Biofunctional Molecules Discovery Centre (SBMDC) School of Medical and Life Sciences Subang Jaya Malaysia.
⁵¹ Biofunctional Molecule Exploratory (BMEX) Research Group, School of Pharmacy Monash University Malaysia Subang Jaya Malaysia.
⁵² Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine University of Technology Sydney Ultimo New South Wales Australia.
⁵³ State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
⁵⁴ Department of Biliary-Pancreatic Surgery, Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
⁵⁵ Cytogenetics Laboratory, Department of Zoology Banaras Hindu University Varanasi Uttar Pradesh India.
⁵⁶ National Research Council Institute of Food Sciences Avellino Italy.
⁵⁷ Department of Veterinary Medicine and Animal Science (DIVAS) University of Milan Lodi Italy.
⁵⁸ Department of Clinical Sciences Polytechnic University of Marche Ancona Italy.
⁵⁹ Joint Laboratory on Food Science, Nutrition, and Intelligent Processing of Foods Polytechnic University of Marche (Italy), Universidad Europea del Atlántico (Spain), and Jiangsu University (China) Ancona Italy.
⁶⁰ International Joint Research, Laboratory of Intelligent Agriculture and Agri-Products Processing Jiangsu University Zhenjiang China.
⁶¹ Department of Pharmacology and Pharmacy The University of Hong Kong Pokfulam Hong Kong SAR.
⁶² Microbiota I-Center Shatin Hong Kong SAR.
⁶³ Department of Medicine and Therapeutics The Chinese University of Hong Kong Shatin Hong Kong SAR.
⁶⁴ Department of Food Science and Technology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China.
⁶⁵ Division of Pharmacognosy, Department of Pharmaceutical Sciences, Faculty of Life Sciences University of Vienna Vienna Austria.
⁶⁶ Archaea Physiology & Biotechnology Group, Department of Functional and Evolutionary Ecology University of Vienna Vienna Austria.
⁶⁷ The NatPro Centre & School of Pharmacy and Pharmaceutical Sciences Trinity College Dublin Dublin Ireland.
⁶⁸ Université Bourgogne Europe/INSERM, 21000 Dijon and PHYNOHA Consulting Fontaine-lès-Dijon France.
⁶⁹ Department of Medical Microbiology Poznań University of Medical Sciences Poznań Poland.
⁷⁰ University of Coimbra, Faculty of Pharmacy, Polo III, Azinhaga de Santa Comba Coimbra Portugal.
⁷¹ Centre for Animal Science Studies (CECA), ICETA University of Porto Porto Portugal.
⁷² Microbiota Lab, Department of Pharmaceutical Microbiology and Bioanalysis Medical University of Warsaw Warsaw Poland.
⁷³ State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology Institute of Microbiology, Guangdong Academy of Sciences Guangzhou China.
⁷⁴ School of Life & Health Sciences Fuyao University of Science & Technology Fuzhou Fujian China.
⁷⁵ Research Group on Food, Nutritional Biochemistry and Health Universidad Europea del Atlántico Santander Spain.
⁷⁶ International Research Center for Food Nutrition and Safety Jiangsu University Zhenjiang China.
⁷⁷ Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes Meknes Morocco.
⁷⁸ Department of Pharmacology and Physiology, Faculty of Medicine University of Montreal Montreal Quebec Canada.
⁷⁹ Research Institute for Future Food The Hong Kong Polytechnic University Hung Hom Hong Kong SAR.
⁸⁰ Department of Food Science and Nutrition The Hong Kong Polytechnic University Hung Hom Hong Kong SAR.
⁸¹ Laboratory of Natural Products and Medicinal Chemistry (LNPMC), Center for Global Health Research, Saveetha Medical College and Hospital Saveetha Institute of Medical and Technical Sciences (SIMATS) Thandalam Chennai India.

PMID: 40469512
PMCID: PMC12130569
DOI: 10.1002/imt2.70028

Enhancing human gut health: Global innovations in dysbiosis management

Reda El Boukhari et al. Imeta. 2025.

. 2025 Apr 13;4(3):e70028.

doi: 10.1002/imt2.70028. eCollection 2025 Jun.

Authors

Affiliations

¹ Chemical Science and Engineering Research Team (ERSIC), Department of Chemistry, Polydisciplinary Faculty of Beni Mellal (FPBM) Sultan Moulay Slimane University (USMS) Beni Mellal Morocco.
² Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences Jastrzębiec Poland.
³ Molecular Chemistry, Materials and Catalysis Laboratory, Faculty of Sciences and Technologies Sultan Moulay Slimane University Beni Mellal Morocco.
⁴ Department of General, Gastroenterologic and Oncologic Surgery Medical University of Warsaw Warsaw Poland.
⁵ Department of Biochemistry and Biotechnology Vasyl Stefanyk Precarpathian National University Ivano-Frankivsk Ukraine.
⁶ Research and Development University Ivano-Frankivsk Ukraine.
⁷ Department of Pharmacy and Institutes for Systems Genetics, Center for High Altitude Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital Sichuan University Chengdu Sichuan China.
⁸ School of Pharmaceutical Sciences Lovely Professional University Phagwara Punjab India.
⁹ Department of Diabetes, Endocrinology and Nutrition Dr. Josep Trueta University Hospital Girona Spain.
¹⁰ CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) Madrid Spain.
¹¹ Integrative Systems Medicine and Biology Group, Girona Biomedical Research Institute (IDIBGI-CERCA) Parc Hospitalari Martí i Julià Salt Spain.
¹² Chair of Pharmaceutical Biology, Faculty of Pharmacy and Chemistry University of Regensburg Germany.
¹³ Center for Evolutionary Biology, School of Life Sciences Fudan University Shanghai China.
¹⁴ Human Phenome Institute, Zhangjiang Fudan International Innovation Center Fudan University Shanghai China.
¹⁵ School of Agriculture Yunnan University Kunming China.
¹⁶ Henan Institute of Medical and Pharmaceutical Sciences Zhengzhou University Zhengzhou China.
¹⁷ Department of Technique and Food Development, Institute of Human Nutrition Sciences Warsaw University of Life Sciences Warsaw Poland.
¹⁸ Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology "Roumen Tsanev" Bulgarian Academy of Sciences Sofia Bulgaria.
¹⁹ Faculty of Medicine The John Paul II Catholic University of Lublin (KUL) Lublin Poland.
²⁰ Department of Cardiology and Adult Congenital Heart Diseases Polish Mother's Memorial Hospital Research Institute (PMMHRI) Lodz Poland.
²¹ Department of Preventive Cardiology and Lipidology Medical University of Lodz (MUL) Lodz Poland.
²² Ciccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine Baltimore Maryland USA.
²³ Anesthesia and Pain Medicine, Department of Medicine, Surgery and Dentistry "Scuola MedicaSalernitana" University of Salerno Baronissi Italy.
²⁴ Department of Critical Care Medicine and Institutes for Systems Genetics Frontiers Science Center for Disease-Related Molecular Network, West China Hospital,Sichuan University Chengdu Sichuan China.
²⁵ Center for High Altitude Medicine, West China Hospital Sichuan University Chengdu Sichuan China.
²⁶ National Institute of Poultry Husbandry Harper Adams University Newport UK.
²⁷ Centre for Metabolism, Obesity and Diabetes Research McMaster University Hamilton Ontario Canada.
²⁸ Division of Endocrinology and Metabolism, Department of Medicine McMaster University Hamilton Ontario Canada.
²⁹ National University of Pharmacy of the Ministry of Health of Ukraine Kharkiv Ukraine.
³⁰ Ludwig Boltzmann Institute Digital Health and Patient Safety Medical University of Vienna Vienna Austria.
³¹ Faculty of Medicine Collegium Medicum Cardinal Stefan Wyszyński University in Warsaw Warsaw Poland.
³² Orthopaedic and Rehabilitation Department Medical University of Warsaw Warsaw Poland.
³³ Department of Genomics MEDFUTURE - Institute for Biomedical Research"Iuliu Hațieganu" University of Medicine and Pharmacy No. 23 Cluj-Napoca Romania.
³⁴ Department of Health Sciences University of Basilicata Potenza Italy.
³⁵ Oral and Maxillofacial Radiology, Applied Oral Sciences and Community Dental Care, Faculty of Dentistry The University of Hong Kong Pokfulam Hong Kong SAR.
³⁶ Amrita School of Biotechnology Amrita Viswa Vidyapeetham Clappana Kerala India.
³⁷ Department of Biosciences Manipal University Jaipur, Dehmi Kala Jaipur Rajasthan India.
³⁸ Department of Pharmacology College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine Bradenton Florida USA.
³⁹ The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA.
⁴⁰ Department of Electrical Engineering and Information Technology George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures Targu Mures Romania.
⁴¹ ESTG-Polytechnic Institute of Leiria Morro do Lena-Alto do Vieiro Leiria Portugal.
⁴² LSRE-LCM-Associate Laboratory in Chemical Engineering University of Porto Porto Portugal.
⁴³ Department of Animal Breeding, Institute of Animal Sciences Warsaw University of Life Sciences - SGGW Warsaw Poland.
⁴⁴ Swiss Paraplegic Research Nottwil Switzerland.
⁴⁵ Institute of Social and Preventive Medicine (ISPM) University of Bern Bern Switzerland.
⁴⁶ College of Pharmacy Ohio State University Columbus Ohio USA.
⁴⁷ Pharmacognosy and Phytotherapy UCL School of Pharmacy London UK.
⁴⁸ Molecular Systems Biology Lab (MOSYS), Department of Functional and Evolutionary Ecology University of Vienna Vienna Austria.
⁴⁹ Vienna Metabolomics Center (VIME) University of Vienna Vienna Austria.
⁵⁰ Sunway Biofunctional Molecules Discovery Centre (SBMDC) School of Medical and Life Sciences Subang Jaya Malaysia.
⁵¹ Biofunctional Molecule Exploratory (BMEX) Research Group, School of Pharmacy Monash University Malaysia Subang Jaya Malaysia.
⁵² Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine University of Technology Sydney Ultimo New South Wales Australia.
⁵³ State Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
⁵⁴ Department of Biliary-Pancreatic Surgery, Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
⁵⁵ Cytogenetics Laboratory, Department of Zoology Banaras Hindu University Varanasi Uttar Pradesh India.
⁵⁶ National Research Council Institute of Food Sciences Avellino Italy.
⁵⁷ Department of Veterinary Medicine and Animal Science (DIVAS) University of Milan Lodi Italy.
⁵⁸ Department of Clinical Sciences Polytechnic University of Marche Ancona Italy.
⁵⁹ Joint Laboratory on Food Science, Nutrition, and Intelligent Processing of Foods Polytechnic University of Marche (Italy), Universidad Europea del Atlántico (Spain), and Jiangsu University (China) Ancona Italy.
⁶⁰ International Joint Research, Laboratory of Intelligent Agriculture and Agri-Products Processing Jiangsu University Zhenjiang China.
⁶¹ Department of Pharmacology and Pharmacy The University of Hong Kong Pokfulam Hong Kong SAR.
⁶² Microbiota I-Center Shatin Hong Kong SAR.
⁶³ Department of Medicine and Therapeutics The Chinese University of Hong Kong Shatin Hong Kong SAR.
⁶⁴ Department of Food Science and Technology, School of Agriculture and Biology Shanghai Jiao Tong University Shanghai China.
⁶⁵ Division of Pharmacognosy, Department of Pharmaceutical Sciences, Faculty of Life Sciences University of Vienna Vienna Austria.
⁶⁶ Archaea Physiology & Biotechnology Group, Department of Functional and Evolutionary Ecology University of Vienna Vienna Austria.
⁶⁷ The NatPro Centre & School of Pharmacy and Pharmaceutical Sciences Trinity College Dublin Dublin Ireland.
⁶⁸ Université Bourgogne Europe/INSERM, 21000 Dijon and PHYNOHA Consulting Fontaine-lès-Dijon France.
⁶⁹ Department of Medical Microbiology Poznań University of Medical Sciences Poznań Poland.
⁷⁰ University of Coimbra, Faculty of Pharmacy, Polo III, Azinhaga de Santa Comba Coimbra Portugal.
⁷¹ Centre for Animal Science Studies (CECA), ICETA University of Porto Porto Portugal.
⁷² Microbiota Lab, Department of Pharmaceutical Microbiology and Bioanalysis Medical University of Warsaw Warsaw Poland.
⁷³ State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology Institute of Microbiology, Guangdong Academy of Sciences Guangzhou China.
⁷⁴ School of Life & Health Sciences Fuyao University of Science & Technology Fuzhou Fujian China.
⁷⁵ Research Group on Food, Nutritional Biochemistry and Health Universidad Europea del Atlántico Santander Spain.
⁷⁶ International Research Center for Food Nutrition and Safety Jiangsu University Zhenjiang China.
⁷⁷ Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes Meknes Morocco.
⁷⁸ Department of Pharmacology and Physiology, Faculty of Medicine University of Montreal Montreal Quebec Canada.
⁷⁹ Research Institute for Future Food The Hong Kong Polytechnic University Hung Hom Hong Kong SAR.
⁸⁰ Department of Food Science and Nutrition The Hong Kong Polytechnic University Hung Hom Hong Kong SAR.
⁸¹ Laboratory of Natural Products and Medicinal Chemistry (LNPMC), Center for Global Health Research, Saveetha Medical College and Hospital Saveetha Institute of Medical and Technical Sciences (SIMATS) Thandalam Chennai India.

PMID: 40469512
PMCID: PMC12130569
DOI: 10.1002/imt2.70028

Abstract

The microbiota, comprising all the microorganisms within the body, plays a critical role in maintaining good health. Dysbiosis represents a condition resulting from an imbalance or alteration of the microbiota. This study comprehensively investigates the patent literature on dysbiosis over the past 20 years.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest. The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in this article.

Figures

**Figure 1**
The global patent landscape of inventions related to dysbiosis. (A) Evolution of the dysbiosis patent publication since 2005 (the year 2024 data are limited to October 28). (B) Current legal status of dysbiosis patent documents. (C) Top 10 dysbiosis patent documents jurisdictions. (D) Top 10 dysbiosis patent documents owners.

**Figure 2**
Dysbiosis‐related data based on relevant diseases, most cited patents and publications, and innovation fields. (A) The most dysbiosis‐associated diseases. (B) The top 10 most cited dysbiosis patent documents. (C) The top 10 scientific publications that are most cited in the dysbiosis patent documents. (D) Innovation fields based on the dysbiosis patent document IPC codes.

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References

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1. Sharma, Kunal , and Kumar Kunal. 2023. “Dysbiosis and Its Varied Impacts.” Eds. Srivastava N., Ibrahim S., Chattopadhyay J., and Arbab M.. in The Gut Microbiota in Health and Disease, Hoboken, NJ: Wiley, pp. 41–54. 10.1002/9781119904786.ch5 - DOI
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1. Tomasello, Giovanni , Mazzola Margherita, Leone Angelo, Sinagra Emanuele, Zummo Giovanni, Farina Felicia, Damiani Provvidenza, et al. 2016. “Nutrition, Oxidative Stress and Intestinal Dysbiosis: Influence of Diet on Gut Microbiota in Inflammatory Bowel Diseases.” Biomedical Papers 160(4): 461–466. 10.5507/bp.2016.052 - DOI - PubMed

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Enhancing human gut health: Global innovations in dysbiosis management

Affiliations

Enhancing human gut health: Global innovations in dysbiosis management

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