Nano optical (bio)sensing platforms for early detection of pediatric cancer

doi:10.1007/s00604-025-07246-2

Review

. 2025 Jun 5;192(7):406.

doi: 10.1007/s00604-025-07246-2.

Nano optical (bio)sensing platforms for early detection of pediatric cancer

Chou-Yi Hsu¹, Anjan Kumar², Prakash Kanjariya³, Asha Rajiv⁴, Aditya Kashyap⁵, Helen Merina Albert⁶, Sumit Pokhriyal^{7

8}, Rajashree Panigrahi⁹

Affiliations

¹ Thunderbird School of Global Management, Arizona State University Tempe Campus, Phoenix, AZ, 85004, USA.
² Department of Electronics and Communication Engineering, GLA University, Mathura, 281406, India.
³ Department of Physics, Faculty of Science, Marwadi University Research Center, Marwadi University, Rajkot-360003, Gujarat, India.
⁴ Department of Physics & Electronics, School of Sciences, JAIN (Deemed to Be University), Bangalore, Karnataka, India.
⁵ Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, 140401, Punjab, India.
⁶ Department of Physics, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India. helenmerina.physics@sathyabama.ac.in.
⁷ Department of Physics, Graphic Era Hill University, Dehradun, India.
⁸ Graphic Era Deemed to Be University, Dehradun, Uttarakhand, India.
⁹ Department of Microbiology, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, 751003, India.

PMID: 40471347
DOI: 10.1007/s00604-025-07246-2

Review

Nano optical (bio)sensing platforms for early detection of pediatric cancer

Chou-Yi Hsu et al. Mikrochim Acta. 2025.

. 2025 Jun 5;192(7):406.

doi: 10.1007/s00604-025-07246-2.

Authors

Chou-Yi Hsu¹, Anjan Kumar², Prakash Kanjariya³, Asha Rajiv⁴, Aditya Kashyap⁵, Helen Merina Albert⁶, Sumit Pokhriyal^{7

8}, Rajashree Panigrahi⁹

Affiliations

¹ Thunderbird School of Global Management, Arizona State University Tempe Campus, Phoenix, AZ, 85004, USA.
² Department of Electronics and Communication Engineering, GLA University, Mathura, 281406, India.
³ Department of Physics, Faculty of Science, Marwadi University Research Center, Marwadi University, Rajkot-360003, Gujarat, India.
⁴ Department of Physics & Electronics, School of Sciences, JAIN (Deemed to Be University), Bangalore, Karnataka, India.
⁵ Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, 140401, Punjab, India.
⁶ Department of Physics, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India. helenmerina.physics@sathyabama.ac.in.
⁷ Department of Physics, Graphic Era Hill University, Dehradun, India.
⁸ Graphic Era Deemed to Be University, Dehradun, Uttarakhand, India.
⁹ Department of Microbiology, IMS and SUM Hospital, Siksha 'O' Anusandhan (Deemed to Be University), Bhubaneswar, 751003, India.

PMID: 40471347
DOI: 10.1007/s00604-025-07246-2

Abstract

Pediatric cancer refers to cancers that occur in children and adolescents, typically defined as those occuring under the age of 18. Although childhood cancers are relatively rare compared to adult cancers, they are a leading cause of death by disease in children. Early detection of childhood cancer is crucial for improving treatment outcomes and survival rates. To detect pediatric cancers in their early stages, the identification of biomarkers can be very helpful. Optical sensors and biosensors, as new analytical devices, can be used as a powerful and non-invasive tool to detect and quantify various cancer-specific biomarkers. Nanomaterials play a transformative role in the development of optical (bio)sensors, enhancing their sensitivity, specificity, and overall performance. Nano optical (bio)sensors provide a non-invasive, swift, and cost-effective method for the early detection of pediatric cancer by identifying cancer-related biomarkers.

Keywords: Biomarker; Biosensor; Early cancer detection; Nanotechnology; Pediatric cancer.

PubMed Disclaimer

Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

References

1. Siegel RL, Miller KD, Fuchs HE, Jemal A (2022) Cancer Statistics, 2022. CA A Cancer J Clin 72:7–33
1. Siegel RL, Miller KD, Jemal A (2020) Cancer Statistics, 2020. CA A Cancer J Clin 70:7–30
1. Bencina G, Oliver E, Meiwald A, Hughes R, Morais E, Schillinger JA, Weston G (2023) Global burden and economic impact of vaccine-preventable cancer mortality. J Clin Oncol 41(16).
1. American Cancer Society, Cancer Facts & Figs. 2020, American Cancer Society, Atlanta, Ga, 2020.
1. Steliarova-Foucher E, Colombet M, Ries LAG et al (2017) International incidence of childhood cancer, 2001–10: a population-based registry study. Lancet Oncol 18(6):719–731 - PubMed - PMC

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions

LinkOut - more resources

Medical
- MedlinePlus Health Information

[1] Siegel RL, Miller KD, Fuchs HE, Jemal A (2022) Cancer Statistics, 2022. CA A Cancer J Clin 72:7–33

[2] Siegel RL, Miller KD, Fuchs HE, Jemal A (2022) Cancer Statistics, 2022. CA A Cancer J Clin 72:7–33

[3] Siegel RL, Miller KD, Jemal A (2020) Cancer Statistics, 2020. CA A Cancer J Clin 70:7–30

[4] Siegel RL, Miller KD, Jemal A (2020) Cancer Statistics, 2020. CA A Cancer J Clin 70:7–30

[5] Bencina G, Oliver E, Meiwald A, Hughes R, Morais E, Schillinger JA, Weston G (2023) Global burden and economic impact of vaccine-preventable cancer mortality. J Clin Oncol 41(16).

[6] Bencina G, Oliver E, Meiwald A, Hughes R, Morais E, Schillinger JA, Weston G (2023) Global burden and economic impact of vaccine-preventable cancer mortality. J Clin Oncol 41(16).

[7] American Cancer Society, Cancer Facts & Figs. 2020, American Cancer Society, Atlanta, Ga, 2020.

[8] American Cancer Society, Cancer Facts & Figs. 2020, American Cancer Society, Atlanta, Ga, 2020.

[9] Steliarova-Foucher E, Colombet M, Ries LAG et al (2017) International incidence of childhood cancer, 2001–10: a population-based registry study. Lancet Oncol 18(6):719–731 - PubMed - PMC

[10] Steliarova-Foucher E, Colombet M, Ries LAG et al (2017) International incidence of childhood cancer, 2001–10: a population-based registry study. Lancet Oncol 18(6):719–731 - PubMed - PMC

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Nano optical (bio)sensing platforms for early detection of pediatric cancer

Affiliations

Nano optical (bio)sensing platforms for early detection of pediatric cancer

Authors

Affiliations

Abstract

Conflict of interest statement

Similar articles

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Medical

Abstract

Conflict of interest statement

Similar articles

References

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Medical