Two-Stage Re-revision for Tuberculosis Affecting a Revision Total Hip Arthroplasty: A Case Report
- PMID: 40472146
- DOI: 10.2106/JBJS.CC.25.00175
Two-Stage Re-revision for Tuberculosis Affecting a Revision Total Hip Arthroplasty: A Case Report
Abstract
Case: A 68-year-old woman presented with pain in her left hip and a discharging sinus for 8 months. Ten months previously, she had undergone a revision total hip arthroplasty (THA) for aseptic loosening of a THA initially performed 30 years ago. This time, she underwent a 2-stage re-revision. Targeted next-generation sequencing identified the organism as Mycobacterium Tuberculosis, followed by antitubercular therapy for 9 months. After a 5-year follow-up, Harris Hip Score was 85%, and there was no evidence of infection or prosthetic loosening.
Conclusion: High index of suspicion and genomic sequencing may be required to identify the organism in tubercular periprosthetic infections.
Keywords: mycobacterium tuberculosis; periprosthetic joint infections; re-revision hip; revision total hip arthroplasty; total hip arthroplasty.
Copyright © 2025 by The Journal of Bone and Joint Surgery, Incorporated.
Conflict of interest statement
Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSCC/C633).
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