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. 2025 Jun 2;33(2):e287081.
doi: 10.1590/1413-785220253302e287081. eCollection 2025.

EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH SYSTEMIC SCLEROSIS TREATED AT A QUATERNARY HOSPITAL IN THE STATE OF SÃO PAULO

Pedro Henrique de Magalhães Tenório  1 , Rafaella Camilo de Oliveira  1 , Matheus Portilho Pinto Ribeiro  1 , Ramon Alves Queiroz  1 , Marcos Felipe Marcatto de Abreu  1
Affiliations

EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH SYSTEMIC SCLEROSIS TREATED AT A QUATERNARY HOSPITAL IN THE STATE OF SÃO PAULO

Pedro Henrique de Magalhães Tenório et al. Acta Ortop Bras. .

Abstract
in English, Portuguese

Objective: To report the profile of patients diagnosed with systemic sclerosis and monitored in a four-year hospital in São Paulo.

Methods: Observational study with 51 patients, mostly composed of women. Descriptive statistics such as mean age, proportions (sex, ethnicity, form of the disease), and correlations between functional scores (HAQ, SHAQ, and Rodnan score) were extracted.

Results: The average age found was 49.96 ± 12.01 years. The time since diagnosis was 11.19 ± 10.16 years. When separated by sex, 25% of men presented the limited form, while 65.9% of women presented the localized form. There was a statistically significant correlation (p-value<0.01) between the Rodnan score and the HAQ score, with a value of 0.36 (CI: 0.09-0.58), as well as with the SHAQ score (value of 0.33; CI: 0.05-0.55, p-value=0.01). When evaluating the correlation between the Rodnan score and the Cochin functional scale, there was a statistically significant correlation (p-value<0.01), with a value of 0.38 (0.12-0.58).

Conclusion: According to the literature, this study showed the highest prevalence in women, and the predominant form is limited. Level of Evidence II; Cohort Study.

Objetivo: Relatar o perfil dos pacientes diagnosticados com esclerose sistêmica e acompanhados em um hospital quartenário paulista.

Métodos: Estudo observacional com 51 pacientes, composto majoritariamente por mulheres. Foram extraídas estatísticas descritivas como idade média, proporções (sexo, etnia, forma da doença) e correlações entre escores funcionais (HAQ, SHAQ e escore de Rodnan).

Resultados: A idade média encontrada foi de 49,96 ± 12,01 anos. O tempo desde o diagnóstico foi de 11,19 ± 10,16 anos. Quando separados por sexo, 25% dos homens apresentaram a forma limitada, enquanto 65,9% das mulheres apresentaram a forma localizada. Houve correlação estatisticamente significante (p-valor<0,01) entre o escore de Rodnan e a pontuação HAQ, com valor de 0,36 (IC: 0,09-0,58), bem como com a pontuação SHAQ (valor de 0,33; IC: 0,05-0,55, p-valor=0.01). Quando avaliada a correlação entre o escore de Rodnan e a escala funcional de Cochin, houve correlação estatisticamente significante (p-valor<0,01), com valor de 0,38 (0,12-0,58).

Conclusão: De acordo com a literatura, este estudo evidenciou a maior prevalência em mulheres e a forma predominante sendo a limitada. Nível de Evidência II; Estudo de Coorte.

Keywords: Epidemiological Profile; Epidemiology; Scleroderma, Systemic.

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Conflict of interest statement

All authors declare no potential conflict of interest related to this article.

Figures

Figure 1
Figure 1. Distribution of forms of the disease by gender.
Figure 2
Figure 2. Distribution of forms of the disease, by self-declared ethnicity.
See this image and copyright information in PMC

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