[Guillain-Barré syndrome as an autoimmune neurological manifestation associated with COVID-19: A review of the literature]
- PMID: 40477413
- PMCID: PMC7914014
- DOI: 10.1016/j.rcreu.2021.01.004
[Guillain-Barré syndrome as an autoimmune neurological manifestation associated with COVID-19: A review of the literature]
Abstract
The coronavirus disease (COVID-19) caused by SARS-CoV-2 has been a challenge for health services around the world. The pandemic has spread widely, with more than 80 million confirmed cases and more than one million deaths globally. There have been many studies to understand all aspects of the disease. Recently, several cases have been reported of patients with Guillain-Barré syndrome associated with COVID-19 as the main manifestation. As it may be one of the first autoimmune neurological diseases triggered by SARS-CoV-2, it is necessary to obtain more information to fully understand the immunopathogenic mechanisms involved in this association.
La enfermedad por coronavirus (COVID-19) producida por el SARS-CoV-2 ha sido un reto para los servicios de salud en todo el mundo. La pandemia se ha extendido ampliamente con más de 80 millones de casos confirmados y más de un millón de muertes a nivel mundial, por lo que ha estado bajo constante investigación para entender todos los aspectos de la enfermedad. Recientemente se han reportado varios casos de pacientes con síndrome de Guillain-Barré asociado a COVID-19 como manifestación principal, convirtiéndola en la primera enfermedad neurológica autoinmune desencadenada por SARS-CoV-2; sin embargo, es necesario obtener más información para entender completamente los mecanismos inmunopatogénicos implicados en esta asociación.
Keywords: COVID-19; Coronavirus; Guillain-Barré syndrome; Rheumatic diseases.
© 2021 Asociación Colombiana de Reumatología. Published by Elsevier España, S.L.U. All rights reserved.
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