The 2024 Three-Strata Baseline Anemia Definition of the Revised IWG-ELN Criteria Dissects Survival in Ruxolitinib-Treated Myelofibrosis Patients

Margherita Maffioli¹, Barbara Mora², Alessandra Iurlo², Elena Maria Elli³, Maria Chiara Finazzi⁴, Mirko Farina⁵, Elisa Rumi^{6

7}, Marianna Caramella⁸, Maria Cristina Carraro⁹, Mariella D'Adda¹⁰, Alfredo Molteni¹¹, Elda Mimiola¹², Francesca Lunghi¹³, Alessandro Vismara¹⁴, Marta Ubezio¹⁵, Maria Chiara Di Chio¹⁶, Michela Anghilieri¹⁷, Daniele Cattaneo^{2

18}, Matteo Giovanni Della Porta^{15

19}, Lorenza Bertù²⁰, Marta Coscia^{1

20}, Francesco Passamonti^{2

18}

Affiliations

¹ Hematology Unit, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.
² Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
³ Hematology Division and Bone Marrow Unit, Fondazione IRCCS, San Gerardo Dei Tintori, Monza, Italy.
⁴ Hematology Division, ASST Papa Giovanni XXIII, Bergamo, Italy.
⁵ Unit of Blood Diseases and Stem Cell Transplantation, ASST Spedali Civili di Brescia, Brescia, Italy.
⁶ Department of Molecular Medicine, University of Pavia, Pavia, Italy.
⁷ Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
⁸ Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
⁹ Hematology and Trasfusional Medicine Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
¹⁰ Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy.
¹¹ Hematology Unit, ASST Cremona, Cremona, Italy.
¹² Department of Hematology and Transfusion Medicine, ASST Mantova, Mantova, Italy.
¹³ Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute and Vita-Salute Hospital, Milan, Italy.
¹⁴ Internal Medicine Department and Hematology Unit, ASST Rhodense, Milan, Italy.
¹⁵ Humanitas Clinical and Research Center-IRCCS, Milan, Italy.
¹⁶ Hematology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
¹⁷ Oncology Department, ASST Lecco, Lecco, Italy.
¹⁸ Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
¹⁹ Department of Biomedical Sciences, Humanitas University, Milan, Italy.
²⁰ Department of Medicine and Surgery, University of Insubria, Varese, Italy.

PMID: 40478635
DOI: 10.1002/ajh.27734

The 2024 Three-Strata Baseline Anemia Definition of the Revised IWG-ELN Criteria Dissects Survival in Ruxolitinib-Treated Myelofibrosis Patients

Margherita Maffioli et al. Am J Hematol. 2025 Sep.

. 2025 Sep;100(9):1656-1659.

doi: 10.1002/ajh.27734. Epub 2025 Jun 6.

Authors

Affiliations

¹ Hematology Unit, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.
² Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
³ Hematology Division and Bone Marrow Unit, Fondazione IRCCS, San Gerardo Dei Tintori, Monza, Italy.
⁴ Hematology Division, ASST Papa Giovanni XXIII, Bergamo, Italy.
⁵ Unit of Blood Diseases and Stem Cell Transplantation, ASST Spedali Civili di Brescia, Brescia, Italy.
⁶ Department of Molecular Medicine, University of Pavia, Pavia, Italy.
⁷ Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
⁸ Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
⁹ Hematology and Trasfusional Medicine Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
¹⁰ Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy.
¹¹ Hematology Unit, ASST Cremona, Cremona, Italy.
¹² Department of Hematology and Transfusion Medicine, ASST Mantova, Mantova, Italy.
¹³ Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute and Vita-Salute Hospital, Milan, Italy.
¹⁴ Internal Medicine Department and Hematology Unit, ASST Rhodense, Milan, Italy.
¹⁵ Humanitas Clinical and Research Center-IRCCS, Milan, Italy.
¹⁶ Hematology Department, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
¹⁷ Oncology Department, ASST Lecco, Lecco, Italy.
¹⁸ Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
¹⁹ Department of Biomedical Sciences, Humanitas University, Milan, Italy.
²⁰ Department of Medicine and Surgery, University of Insubria, Varese, Italy.

PMID: 40478635
DOI: 10.1002/ajh.27734

No abstract available

Keywords: anemia; myelofibrosis; prognosis; ruxolitinib.

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The 2024 Three-Strata Baseline Anemia Definition of the Revised IWG-ELN Criteria Dissects Survival in Ruxolitinib-Treated Myelofibrosis Patients

Affiliations

The 2024 Three-Strata Baseline Anemia Definition of the Revised IWG-ELN Criteria Dissects Survival in Ruxolitinib-Treated Myelofibrosis Patients

Authors

Affiliations

Publication types

Grants and funding

LinkOut - more resources

Full Text Sources