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. 2025 Jun 4;30(13):103560.
doi: 10.1016/j.jaccas.2025.103560.

Giant Obstructing Left Ventricular Dedifferentiated Liposarcoma

Michele Dell'Aquila  1 , Joost Ter Woorst  2 , Ferdi Akca  3
Affiliations

Giant Obstructing Left Ventricular Dedifferentiated Liposarcoma

Michele Dell'Aquila et al. JACC Case Rep. .

Abstract

We present the case of a 52-year-old woman diagnosed with new-onset atrial fibrillation due to an intracardiac mass found incidentally. She underwent successful surgical resection of an obstructing, paravalvular, dedifferentiated liposarcoma in the left ventricle and received a mitral valve replacement. The patient underwent adjuvant radiotherapy. Follow-up is ongoing.

Keywords: cardiac dedifferentiated liposarcoma; cardiac sarcoma; cardiac tumor.

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Conflict of interest statement

Funding Support and Author Disclosures The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Cardiac Computed Tomography Axial slices showing left ventricular mass.
Figure 2
Figure 2
Resected Dedifferentiated Liposarcoma Fragments Multiple fragments of the resected dedifferentiated liposarcoma.
See this image and copyright information in PMC

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