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Review
. 2025 Jul;55(8):1755-1760.
doi: 10.1007/s00247-025-06283-6. Epub 2025 Jun 7.

Pediatric subcutaneous panniculitis-like T-cell lymphoma: a case report and review of the literature

Affiliations
Review

Pediatric subcutaneous panniculitis-like T-cell lymphoma: a case report and review of the literature

Haiying Zhou et al. Pediatr Radiol. 2025 Jul.

Abstract

Subcutaneous panniculitis-like T-cell lymphoma is a distinct entity of cutaneous malignant lymphoma. We report an atypical presentation of subcutaneous panniculitis-like T-cell lymphoma in a 3-month-old infant, incidentally diagnosed with a right chest wall mass devoid of ulceration, tenderness, or systemic symptoms (fever). Due to unresectability, the child underwent five cycles of chemotherapy. This rare case highlights the importance of considering subcutaneous panniculitis-like T-cell lymphoma in young patients with image findings suggestive of subcutaneous fat involvement. Timely diagnosis via recognition and biopsy is paramount for guiding management strategies.

Keywords: Child; Panniculitis; Subcutaneous panniculitis-like T-cell lymphoma; Ultrasonography.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee. Consent for publication: Informed consent was obtained from the parents/legal guardians of all the participants included in the study. Conflicts of interest: The authors declare no competing interests.

References

    1. Willemze R, Jansen PM, Cerroni L et al (2008) Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC Cutaneous Lymphoma Group study of 83 cases. Blood 111:838–845
    1. Rutnin S, Porntharukcharoen S, Boonsakan P (2019) Clinicopathologic, immunophenotypic, and molecular analysis of subcutaneous panniculitis-like T-cell lymphoma: a retrospective study in a tertiary care center. J Cutan Pathol 46:44–51. https://doi.org/10.1111/cup.13377 - DOI
    1. Guitart J, Mangold AR, Martinez-Escala ME et al (2022) Clinical and pathological characteristics and outcomes among patients with subcutaneous panniculitis-like T-cell lymphoma and related adipotropic lymphoproliferative disorders. JAMA Dermatol 158:1167–1174. https://doi.org/10.1001/jamadermatol.2022.3347 - DOI
    1. Jeong SI, Lim HS, Choi YR et al (2013) Subcutaneous panniculitis-like T-cell lymphoma of the breast. Korean J Radiol 14:391–394. https://doi.org/10.3348/kjr.2013.14.3.391 - DOI
    1. Sy AN, Lam TP, Khoo US (2005) Subcutaneous panniculitis-like T-cell lymphoma appearing as a breast mass: a difficult and challenging case appearing at an unusual site. J Ultrasound Med 24:1453–1460. https://doi.org/10.7863/jum.2005.24.10.1453 - DOI

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