Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 May 8;17(5):e83746.
doi: 10.7759/cureus.83746. eCollection 2025 May.

Pneumocystis Pneumonia in a Non-AIDS Patient

Adel N Shalabi  1   2 , Taha Saleem  2 , Neel H Patel  2 , Lauren E Blewett  1 , James L Crowe  3
Affiliations
Case Reports

Pneumocystis Pneumonia in a Non-AIDS Patient

Adel N Shalabi et al. Cureus. .

Abstract

We present a unique case of Pneumocystis jirovecii pneumonia (PCP) in a patient with HIV. Both treated and untreated HIV patients are susceptible to opportunistic pathogens. Depending on the patient's underlying cluster of differentiation 4 T-cell (CD4 T-cell) count, HIV is associated with a wide range of infections. Historically, PCP has been observed in HIV patients with AIDS or in those receiving immunosuppressive therapy. However, it should remain a differential diagnosis in patients who present with comorbidities and symptoms of acute lung disease.

Keywords: hiv cd4 t-cells; hiv diseases; hiv infections; human immuno-deficiency virus (hiv); non-aids pcp; opportunist infections in hiv; pjp in hiv; pneumocystis carinii pneumonia; pneumocystis jiroveci pneumonia; pneumocystis pneumonia (pcp).

PubMed Disclaimer

Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. High-resolution CT and chest X-ray demonstrate ground-glass opacities and diffuse interstitial infiltrates in a patient with PCP.
Courtesy of Leonard J. Chabert Medical Center. PCP: Pneumocystis jirovecii pneumonia.
See this image and copyright information in PMC

References

    1. A rare case of Pneumocystis pneumonia in HIV patient on glucocorticoid. Rehman U, Farhan K, Shahnawaz W, Khalid MZ, Neupane K. Cureus. 2021;13:0. - PMC - PubMed
    1. Truong J, Ashurst JV. Treasure Island, FL: StatPearls Publishing; 2024. Pneumocystis jirovecii pneumonia. - PubMed
    1. How to diagnose and treat a patient without human immunodeficiency virus infection having Pneumocystis jirovecii pneumonia? Hänsel L, Schumacher J, Denis B, Hamane S, Cornely OA, Koehler P. Clin Microbiol Infect. 2023;29:1015–1023. - PubMed
    1. [Role of glucocorticoids in pneumocystis pneumonia in patients with non-HIV infection/AIDS (HIV/AIDS) and related mechanisms] Guo YW, Li HC. Zhonghua Jie He He Hu Xi Za Zhi. 2023;46:1249–1253. - PubMed
    1. Diagnosing Pneumocystis jirovecii pneumonia: a review of current methods and novel approaches. Bateman M, Oladele R, Kolls JK. Med Mycol. 2020;58:1015–1028. - PMC - PubMed

Publication types

LinkOut - more resources