Public-private partnerships in tackling sickle cell disease in Uganda: a narrative review

Abstract

Sickle cell disease (SCD) remains a critical public health challenge in Uganda, where the prevalence is among the highest globally, and particularly affecting children. The management of SCD is complicated by limited healthcare infrastructure, a shortage of trained healthcare professionals, and widespread stigmatization. Public-private partnerships (PPPs) have emerged as a strategic solution to these challenges, leveraging the strengths of both the public and private sectors to improve access to care, enhance patient outcomes, and raise public awareness. This narrative review examines the role of PPPs in tackling SCD in Uganda, focusing on key areas such as health infrastructure development, capacity building for healthcare workers, and access to essential medications and treatments. The review highlights successful models of PPPs that have facilitated the establishment of specialized sickle cell clinics, the implementation of cost-effective screening programs, and community engagement initiatives aimed at reducing stigma and promoting early diagnosis. These partnerships have significantly contributed to improving the quality of care for individuals with SCD, particularly in high-prevalence regions.

Keywords: Uganda; community engagement; disease management; healthcare; public–private partnerships; sickle cell disease.

Figure 1.

Challenges in SCD management in Uganda.

Figure 2.

Public–private partnership in SCD management in Uganda.