Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 May 8:24:100978.
doi: 10.1016/j.resplu.2025.100978. eCollection 2025 Jul.

Complete atrioventricular block during neonatal intubation: a case report

Affiliations
Case Reports

Complete atrioventricular block during neonatal intubation: a case report

Justine Dauby et al. Resusc Plus. .

Abstract

Preterm infants often experience side effects from intubation. Desaturation and sinus bradycardia are frequent. Atropine as premedication mitigates these risks. We report the occurrence of severe bradycardia related to atrioventricular block during intubation. The infant experienced severe bradycardia not responsive to effective endotracheal ventilation. The electrocardiogram trace displayed an initial 2:1 Mobitz II block with a rapid progression to complete atrioventricular block. Congenital atrioventricular block is mostly related to atrioventricular node lesions by maternal anti-SSA/anti-SSB antibodies, but, in some cases, atrioventricular block may be paroxysmal and vagally mediated. Although most rhythm disturbances secondary to intubation are sinus bradycardias, other bradyarhythmia, such as atrioventricular block, should be considered and treated rapidly. Clues for non-sinus bradycardia include initial sharp decrease in heart rate, and a fixed low heart rate despite adequate ventilation.

Keywords: Atrioventricular block; Atropine; Bradycardia; Intubation; Neonate.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Two minutes of continuous ECG recorded during the procedure. (a) Atropine-related sinus tachycardia. (b) 1:2 Atrio-ventricular block followed by 3:1 and 4:1 blocks.(c) Complete AV block with ventricular bradycardia and progressively slowing atrial beats.

References

    1. Neches S.K., Brei B.K., Umoren R., et al. Association of full premedication on tracheal intubation outcomes in the neonatal intensive care unit: an observational cohort study. J Perinatol. 2023;43:1007–1014. doi: 10.1038/s41372-023-01632-5. - DOI - PubMed
    1. Foglia E.E., Ades A., Sawyer T., et al. Neonatal intubation practice and outcomes: an international registry study. Pediatrics. 2019;143(1) doi: 10.1542/peds.2018-0902. - DOI - PMC - PubMed
    1. Durrmeyer X., Walter-Nicolet E., Chollat C., et al. Premedication before laryngoscopy in neonates: Evidence-based statement from the French society of neonatology (SFN) Front Pediatr. 2023;10 doi: 10.3389/fped.2022.1075184. - DOI - PMC - PubMed
    1. Barrington K. Premedication for endotracheal intubation in the newborn infant. Paediatr Child Health. 2011;16(3):159–171. doi: 10.1093/pch/16.3.159. - DOI - PMC - PubMed
    1. Jones P., Dauger S., Denjoy I., et al. The effect of atropine on rhythm and conduction disturbances during 322 critical care intubations. Pediatr Crit Care Med. 2013;14:e289–e297. doi: 10.1097/PCC.0b013e31828a8624. - DOI - PubMed

Publication types

LinkOut - more resources