Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Jun 5:18:291-295.
doi: 10.2147/MDER.S513233. eCollection 2025.

Case Report: Treating Atrial Fibrillation with the Neubie Direct Current Electrical Stimulation

Affiliations
Case Reports

Case Report: Treating Atrial Fibrillation with the Neubie Direct Current Electrical Stimulation

Richard Ennis et al. Med Devices (Auckl). .

Abstract

Introduction: A novel Neuro-Bio-Electric-Stimulation device (Neubie, Neufit, Austin, Texas, USA) using Direct Current (DC) has been used to treat various neurological conditions (ALS, MS, peripheral neuropathy, chronic pain) and functional limitations such as limited range of motion. One method, called the Master Reset Protocol, is thought to stimulate the vagus nerve system, impacting heart rate, digestion and other vital systems.

Purpose: We used the Master Reset Protocol on a subject experiencing paroxysmal Atrial Fibrillation (AFib) to assess whether this treatment might be effective in reversing a cardiac arrhythmia.

Subject and methods: A single subject is reported in this Case Report. The subject is a 62-year-old healthy, athletic male, 6'2″ tall, 165 lbs. with a good diet and is not obese nor has other exacerbating underlying conditions related to heart disease. The subject experiences arrhythmia approximately 1-2 times per month lasting generally 3 or more days per the subject. The Master Reset Method was initiated within 12 hours of arrhythmia onset, and arrhythmia before and after treatment was confirmed through subject observation and confirmed with pulse readings. A total of ten treatments were conducted over 7 months.

Results: Reversal of arrhythmia was confirmed during or within 24 hours of treatment with DC application for all 10 treatments (100%). Two of the more severe cases of AFib required two treatments on the same day with confirmed reversal of AFib.

Conclusion: Treatment with Direct Current suggests a good correlation with reversal of arrhythmia. Further studies are planned to determine if similar, regular, treatments can be effective in preventing arrhythmia.

Keywords: AFib; cardiac arrhythmia; direct current; electrical stimulation; vagus nerve.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Similar articles

References

    1. Lippi G, Sanchis-Gomar F, Cervellin G. Global Epidemiology of Atrial Fibrillation: an Increasing Epidemic and Public Health Challenge. Int J Stroke. 2020;15(9):NP11–NP12. - PubMed
    1. https://www.nhlbi.nih.gov/health/atrial-fibrillation/types.
    1. Tzeis S, Gerstenfeld EP, Kalman J, et al. European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation. J Inter Card Electrophysiol. 2024;67(5):921–1072. - PubMed
    1. Mendez MM, Hsu M-C, Yuan J-T, Lynn K-S. A Heart Rate Variability-Based Paroxysmal Atrial Fibrillation Prediction System. Appl Sci. 2022;12(5):2387. doi:10.3390/app12052387 - DOI
    1. Sagris M, Vardas EP, Theofilif P, Antonopoulos AS, Oikonomou E, Tousoulis D. Atrial Fibrillation: pathogenesis, Predisposing Factors, and Genetics. Int J Mol Sci. 2022;23(6):6. doi:10.3390/ijms23010006 - DOI - PMC - PubMed

Publication types

LinkOut - more resources