Bidirectional link between mood disorders and diabetic retinopathy
- PMID: 40495843
- PMCID: PMC12146998
- DOI: 10.5498/wjp.v15.i5.102540
Bidirectional link between mood disorders and diabetic retinopathy
Abstract
The recently published article by Gao et al identifies risk factors for anxiety and depression in patients with diabetic retinopathy. We supplement that there is pathophysiological evidence to show a complex and possibly bidirectional relation between diabetes, diabetic retinopathy, and mood disorders, especially depression. Longitudinal studies may strengthen proof of a causal relationship between these diseases. A better understanding can help in the holistic management of these patients.
Keywords: Anxiety; Bidirectional; Correlation; Depression; Diabetes; Diabetic retinopathy; Mood disorders.
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Conflict of interest statement
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
References
-
- Chen X, Lu L. Depression in Diabetic Retinopathy: A Review and Recommendation for Psychiatric Management. Psychosomatics. 2016;57:465–471. - PubMed
-
- Duarte-Silva E, de Melo MG, Maes M, Filho AJMC, Macedo D, Peixoto CA. Shared metabolic and neuroimmune mechanisms underlying Type 2 Diabetes Mellitus and Major Depressive Disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2021;111:110351. - PubMed
Publication types
LinkOut - more resources
Full Text Sources