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. 2025 May 20:8:100148.
doi: 10.1016/j.crphys.2025.100148. eCollection 2025.

Sex-related differences in the acute physiological response to a high-intensity CrossFit® workout

Affiliations

Sex-related differences in the acute physiological response to a high-intensity CrossFit® workout

Manoel Rios et al. Curr Res Physiol. .

Abstract

CrossFit® is popular form of fitness training but the cardiorespiratory, hemodynamic and metabolic responses have not been well characterised. We compared responses to a short Fran CrossFit® session (consisting of three rounds of 21, 15 and 9 front squat to press overhead and pull-ups) between sexes to evaluate differences in acute exercise effects. Twenty-five (15 males and 10 females) trained participants performed a prescribed Fran session at maximal exertion. Cardiorespiratory variables were assessed at baseline, during and post-exercise. The rating of perceived exertion, blood pressure, blood lactate and glucose concentrations were measured at baseline and in the recovery period. The males completed Fran session in less time (males 177 ± 15 vs females 206 ± 27 s; mean ± SD), resulting in higher peak oxygen uptake values (50.1 ± 3.3 vs 46.4 ± 2.2 mL kg -1 min -1), heart rate (187 ± 6 vs 180 ± 3 b min-1) and percentage heart rate (96 ± 3 vs 93 ± 1 %) compared to females. In addition, elevated systolic blood pressure (male 154 ± 8 vs females 149 ± 10 mmHg), double product (27,050 ± 1504 vs 25,999 ± 2253 mmHg b∙min -1), blood lactate (15.7 ± 1.7 vs 14.6 ± 2.0 mmol L-1) and glucose (132 ± 15 vs 132 ± 14 mg dL-1) values were observed in both sexes post-exercise. The substantial metabolic demands associated with a Fran session can yield similar elevations in cardiorespiratory and hemodynamic responses in both sexes, meeting the criteria for developing cardiorespiratory fitness. Complementarily, these results suggest that researchers and coaches can use the Fran session at maximal effort to assess and monitor crossfitters' training status throughout a CrossFit® season, guiding efforts towards excellence in this demanding sport.

Keywords: Cardiovascular; Exercise; Hemodinamic; Physical fitness; Pulmonary; Recovery.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Cardiorespiratory variables assessed during baseline, Fran and post-exercise for males (blue) and females (pink). ∗ differences from baseline in the same sex (p ≤ 0.05). + differences from Fran in the same sex (p ≤ 0.05). ∗∗ difference between the sexes at the same time point (p ≤ 0.05). Individual and mean values.
Fig. 2
Fig. 2
Hemodynamics variables assessed during baseline and post-exercise for males (blue) and females (pink). ∗ differences from baseline in the same sexes (p ≤ 0.05). + differences from Fran in the same sexes (p ≤ 0.05). Individual and mean values.
Fig. 3
Fig. 3
Metabolic variables and perceived effort assessed during baseline and post-exercise for males (blue) and females (pink). ∗ differences from baseline in the same sexes (p ≤ 0.05). + differences from Fran in the same sexes (p ≤ 0.05). Individual and mean values.

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