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Case Reports
. 2025 May 23;20(8):3982-3985.
doi: 10.1016/j.radcr.2025.04.114. eCollection 2025 Aug.

Neuropsychiatric symptoms revealing Morgagni-Stewart-Morel syndrome: About 2 cases

Mehdi El Azouzi  1 , Salah Ben El Hend  2 , Amine Bentahar  3 , Abdelghani El Fikri  2
Affiliations
Case Reports

Neuropsychiatric symptoms revealing Morgagni-Stewart-Morel syndrome: About 2 cases

Mehdi El Azouzi et al. Radiol Case Rep. .

Abstract

Internal frontal hyperostosis is a proliferation of the frontal bone that can occur in isolation or in association with neuropsychiatric, metabolic and endocrine symptoms, which together form Morgagni-Stewart-Morel syndrome. In this regard, we report the case of 2 patients meeting the criteria for this syndrome which is revealed by neuropsychiatric manifestations, and a review of the literature is carried out focusing on its pathophysiology.

Keywords: Internal frontal hyperostosis; Metabolic disorders; Morgagni-Stewart-Morel syndrome; Neuropsychiatric manifestations.

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Figures

Fig 1:
Fig. 1
(Case 1) Computed tomography scan in axial (A) and Coronal (B) view revealing bilateral, irregular thickening of the internal table of the frontal bone (arrow), associated with significant thickening of the diploe without parenchymal or vascular lesions.
Fig 2:
Fig. 2
(Case 2) Computed tomography scan in axial (A) and Coronal (B) view revealing bilateral, irregular thickening of the internal table of the frontal bone (arrow), associated with significant thickening of the diploe without parenchymal or vascular lesions.
See this image and copyright information in PMC

References

    1. Attanasio F., Granziera S., Giantin V., et al. Full penetrance of Morgagni-Stewart-Morel syndrome in a 75-year-old woman: case report and review of the literature. J Clin Endocrinol Metab. 2013;98(2):453–457. - PubMed
    1. Paris C., Pangnarind V., Cambon A., et al. Céphalées révélatrices d’un syndrome de Morgagni-Stewart-Morel: une observation. Rev Médecine Interne. 2017;38:A209–A210.
    1. Nallegowda M., Singh U., Khanna M., Yadav S., Choudhary A., Thakar A. Morgagni Stewart morel syndrome additional features. Neurol India. 2005;53:117–119. - PubMed
    1. Morgagni G.B. Adversaria anatomica VI: Animadversio LXXIV. Typographia Seminarii (Giovanni Battista Volpato); Padua: 1719.
    1. Stewart R.M. Localized cranial hyperostosis in the insane. J Neurol Psychopathol. 1928;8(32):321–331. - PMC - PubMed

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