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Practice Guideline
. 2025 Jun;23(6):255-269.
doi: 10.6004/jnccn.2025.0027.

Thymomas and Thymic Carcinomas, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Gregory J Riely  1 , Douglas E Wood  2 , Billy W Loo  3 , Dara L Aisner  4 , Wallace Akerley  5 , Jessica R Bauman  6 , Ankit Bharat  7 , Joe Y Chang  8 , Lucian R Chirieac  9 , Malcolm DeCamp  10 , Aakash Desai  11 , Thomas J Dilling  12 , Jonathan Dowell  13 , Gregory A Durm  14 , Scott Gettinger  15 , Travis E Grotz  16 , Matthew A Gubens  17 , Aditya Juloori  18 , Rudy P Lackner  19 , Michael Lanuti  20 , Jules Lin  21 , Christine M Lovly  22 , Fabien Maldonado  22 , Daniel Morgensztern  23 , Trey C Mullikin  24 , Thomas Ng  25 , Dawn Owen  16 , Dwight H Owen  26 , Sandip P Patel  27 , Tejas Patil  4 , Patricio M Polanco  13 , Jonathan Riess  28 , Theresa A Shapiro  29 , Aditi P Singh  30 , James Stevenson  31 , Alda Tam  8 , Tawee Tanvetyanon  12 , Jane Yanagawa  32 , Stephen C Yang  29 , Edwin Yau  33 , Kristina Gregory  34 , Lisa Hang  34
Affiliations
Practice Guideline

Thymomas and Thymic Carcinomas, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology

Gregory J Riely et al. J Natl Compr Canc Netw. 2025 Jun.

Abstract

Thymomas and thymic carcinomas are rare mediastinal tumors that originate in the thymus. Patients with thymoma may experience symptoms associated with autoimmune paraneoplastic diseases (such as myasthenia gravis), which typically do not occur in patients with thymic carcinoma. The NCCN Guidelines for Thymomas and Thymic Carcinomas provide guidance for the diagnosis, treatment, and surveillance of patients with thymoma and thymic carcinoma. Involvement of a multidisciplinary team with experience treating thymomas and thymic carcinomas is highly recommended.

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