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Review
. 2025 Oct 1:252:88-92.
doi: 10.1016/j.amjcard.2025.06.009. Epub 2025 Jun 9.

Renal Denervation: Patient Selection and When to Refer

Raven A Voora  1 , Michael J Bloch  2 , Naomi Dl Fisher  3
Affiliations
Review

Renal Denervation: Patient Selection and When to Refer

Raven A Voora et al. Am J Cardiol. .

Abstract

The US FDA approved Renal Denervation for hypertension treatment in November 2023. Regardless of the methodology used to denervate, most but not all people had a clinically significant reduction in blood pressure in the months following the procedure. In this review we summarize the current data informing patient selection, and provide guidance on when to refer potential patients for consideration of this therapy in the management of uncontrolled hypertension.

Keywords: hypertension; patient referral; patient selection; renal denervation.

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Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: RV – Consultant to Medtronic and Mineralys Therapeutics. MJB – Steering committee member for Recor Medical; Consultant to Medtronic. NDLF – Consultant to Recor Medical, Aktiia, Alnylam, Astra Zeneca and Medtronic; Research funding from Recor Medical.

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