Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 May 24:46:e00716.
doi: 10.1016/j.crwh.2025.e00716. eCollection 2025 Jun.

Pyogenic granuloma gravidarum: A case report

Affiliations
Case Reports

Pyogenic granuloma gravidarum: A case report

Ruth S Goh et al. Case Rep Womens Health. .

Abstract

Pyogenic granuloma gravidarum (PGG) is a benign fibrovascular lesion arising during pregnancy. This report concerns a woman in her third trimester of pregnancy with recurrent left epistaxis and a swelling in her left nostril. She was diagnosed with PGG via magnetic resonance imaging (MRI) and nasoendoscopy. The lesion was managed conservatively and the neonate was delivered without complication at 37 weeks of gestation. Evidence shows that MRI is superior to computerised tomography (CT) in the assessment of soft-tissue masses, but there is a paucity of MRI PGG imaging in the literature. This report shows that MRI, together with the clinical context, is adequate to make a diagnosis of PGG. This was a rare case of a nasal lesion that was allowed to involute conservatively, hence avoiding the potential complications of surgery. This appears to be the first published report to include a follow-up to a successful second pregnancy and delivery without the recurrence of PGG.

Keywords: Benign fibrovascular lesion; Lobular capillary haemangioma; Nasal pregnancy tumour; Pyogenic granuloma gravidarum.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Post-contrast T1-weighted sagittal image showing an intensely enhancing nodule abutting the inferior turbinate. Flow voids within the lesion allude to its vascular nature.

References

    1. Alalula L.S., Arafat A., Alhedaithy Riyadh, Elkrim M. Intranasal lobular capillary hemangioma with multiple sites of origin during pregnancy: A case report and literature review. Case Rep. Otolaryngol. 2018;2018:1–5. doi: 10.1155/2018/7413918. - DOI - PMC - PubMed
    1. Choudhary S., MacKinnon C.A., Morrissey G., Tan S.T. A case of giant nasal pyogenic granuloma gravidarum. J. Craniofac. Surg. 2005;16(2):319–321. doi: 10.1097/00001665-200503000-00022. - DOI - PubMed
    1. Jones J., Nguyen An Tuyet, Tabaee Abtin. Pyogenic granuloma (pregnancy tumor) of the nasal cavity. A case report. PubMed. 2000;45(9):749–753. - PubMed
    1. Oakes R.E., Frampton S.J., Scott Pamela Moyers. Granuloma gravidarum: management. J. Obstet. Gynaecol. 2012;32(8):805. doi: 10.3109/01443615.2012.709287. - DOI - PubMed
    1. Zarrinneshan A., Zapanta P.E., Wall S. Nasal pyogenic granuloma. Otolaryngol. Head Neck Surg. 2007;136(1):130–131. doi: 10.1016/j.otohns.2006.07.031. - DOI - PubMed

Publication types

LinkOut - more resources